2021
DOI: 10.1111/trf.16257
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Quality of evidence‐based guidelines for platelet transfusion and use: A systematic review

Abstract: Background: Guidelines for platelet (PLT) transfusion are an important source of information for clinicians. Although guidelines intend to increase consistency and quality of care, variation in methodology and recommendations may exist that could impact the value of a guideline. We aimed to determine the quality of existing PLT transfusion guidelines using the Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument and to describe the inconsistencies in recommendations. Study Design and Metho… Show more

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Cited by 11 publications
(6 citation statements)
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“…Of the 110 included SRs, 11 were SRs embedded in evidence‐based guideline projects [ 9 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 ], and three were overviews of reviews concerning the management of traumatic brain injury [ 27 , 28 ] or trauma‐induced coagulopathy [ 29 ]. The remainder were SRs of primary research, either experimental studies, observational studies or both.…”
Section: Resultsmentioning
confidence: 99%
“…Of the 110 included SRs, 11 were SRs embedded in evidence‐based guideline projects [ 9 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 ], and three were overviews of reviews concerning the management of traumatic brain injury [ 27 , 28 ] or trauma‐induced coagulopathy [ 29 ]. The remainder were SRs of primary research, either experimental studies, observational studies or both.…”
Section: Resultsmentioning
confidence: 99%
“…[13][14][15] Although clinical practice guidelines recommend prophylactic platelet transfusions, 3 the evidence supporting platelet transfusions in specific clinical indications has been rated as low/verylow quality by GRADE methodology and there are inconsistent recommendations across various guidelines. 16,17 Although Patient Blood Management (PBM) initiatives appear to be effective in restricting RBC and plasma transfusions nationwide, targeted interventions are needed for platelets.…”
Section: Resultsmentioning
confidence: 99%
“…A systematic review of evidence-based clinical practice guidelines pertaining to platelet transfusions identified seven recent studies of variable quality 273 . Considering the inconsistencies between guidelines and the fact that none of them included recommendations for IPDs, no statement can be made regarding the indication of platelet transfusion in patients with IBDs.…”
Section: Discussionmentioning
confidence: 99%