Quality of Emergence from Anesthesia and Incidence of Vomiting with Remifentanil in a Pediatric Population

Mc, Pinsker; Carroll, NV

doi:10.1097/00000539-199907000-00013

Cited by 10 publications

(3 citation statements)

References 6 publications

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“…When comparing remifentanil and alfentanil, there was no significant difference between the incidence of POV (31% vs. 26%) in strabismus surgery (7). Comparing the groups with and without remifentanil under desflurane anesthesia, the incidence of POV was not different even though the administration of desflurane was different (8). Oh et al ( 9) evaluated the incidence of PONV after pediatric strabismus surgery with sevoflurane or remifentanil-sevoflurane, both using 50% N 2 O/O 2 .…”

Section: Resultsmentioning

confidence: 99%

Effect of Remifentanil on Postoperative Vomiting After Strabismus Surgery in Preschool Children: A Prospective Randomized Controlled Trial

Lee

et al. 2022

Anesth Pain Med

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Background: Strabismus surgery and the use of opioid are risk factors of postoperative vomiting. We evaluated whether there is a dose-dependent effect of remifentanil on the incidence of postoperative vomiting. Methods: Sixty pediatric patients who were scheduled for strabismus surgery were enrolled. Patients were randomly divided into three groups; Group H (high-dose remifentanil group), Group L (low-dose remifentanil group), and Group C (control group). After endotracheal intubation, patients in the Group H and L received an intravenous bolus dose of remifentanil of 1.0 μg/kg and 0.5 μg/kg over 2 min, respectively. Group H and L patients received a continuous infusion of remifentanil (0.1 μg/kg/min) during the surgery. The patients in Group C did not have any dose of remifentanil. Intravenous fentanyl (1 µg/kg) was administered to the patients for postoperative pain control. Results: The primary outcome was a difference of the incidence of postoperative vomiting within 24 hours after surgery. There was no significant difference in incidence of postoperative vomiting between three groups. The degree of emergence agitation and postoperative pain did not show any significant difference between three groups. Conclusions: The intraoperative administration of remifentanil did not show dose-dependent effect on postoperative vomiting in pediatric strabismus surgery.

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Section: Resultsmentioning

confidence: 99%

Effect of Remifentanil on Postoperative Vomiting After Strabismus Surgery in Preschool Children: A Prospective Randomized Controlled Trial

Lee

et al. 2022

Anesth Pain Med

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“…For example, one study reported that the side effects of remifentanil were not more than nonopioid drugs. [ 23 ] While others demonstrated that complications such as breathing and conscious reduction were observed in the use of remifentanil. [ 8 9 ] The combination of remifentanil with midazolam increases forgetfulness after the procedure compared to midazolam alone.…”

Section: Discussionmentioning

confidence: 99%

Comparative evaluation of bispectral index system after sedation with midazolam and propofol combined with remifentanil versus ketamine in uncooperative during dental procedures

et al. 2016

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Background:Proper analgesic agents should be used in combination with sedative agents. Remifentanil is a synthetic narcotic/analgesic agent with a short duration effect and decreases the risk of apnea during recovery. Bispectral index system (BIS) is a new noninvasive technique for the evaluation of the depth of sedation. The aim of present clinical trial was to evaluate and compare the efficacy of intravenous sedation with propofol/midazolam/remifentanil (PMR) in comparison to propofol/midazolam/ketamine (PMK) for dental procedures in children 3-7 years of age.Materials and Methods:In this clinical trial, 32 healthy uncooperative children who were candidates for dental treatments under sedation were randomly divided into two groups. Intravenous sedation was induced with PMR in one group and with PMK in the other group. After injection and during procedure BIS index, heart rate and respiratory rate, blood pressure, and oxygen saturation was evaluated every 5 min. After the procedure, recovery time was measured. Data were analyzed with ANOVA, Friedman, Wilcoxon, and t-test.Results:The BIS value was significantly low in ketamin group (P = 0.003) but respiratory rates and heart rates were same in both groups with no statistical difference (P = 0.884, P = 0.775). The recovery time was significantly shorter in remifentanil group (P = 0.008 and P = 0.003).Conclusion:It can be concluded that intravenous sedation technique with PMR combination induces effective and safe sedation, with less pain and more forgetfulness and a shorter recovery time for children 3-7 years of age during dental procedures.

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“…Es wird von unspezifischen Plasma-und Gewebsesterasen metabolisiert und zeigt bei Erwachenen Plasmaeliminationshalbwertszeiten von 3-10 min. Es ist für Kinder ab einem Jahr zugelassen und über seine Anwendung bei pädiatrischen Narkosen liegen eine Reihe von Studien vor [8,13,14,15,28,71,99,100]. Seine Eliminationshalbwertszeit entspricht der von Erwachsenen [14], und es scheint auch nach längerer Anwendung nicht zu kumulieren.…”

Section: Opioideunclassified

Anästhesiologisches Management zur Endoskopie der Atemwege bei Kindern

Machotta

2002

Der Anaesthesist

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We have developed a modern strategy for the anaesthetic management of the pediatric airway using anaesthetic drugs such as sevoflurane, propofol, mivacurium and remifentanil, together with new techniques including the laryngeal mask. This strategy provides optimal conditions for the examiner and maximum safety for the pediatric patient. The endoscopic investigation of pediatric airways has become important for the diagnosis and treatment of many pediatric diseases, and is often performed with the support of a pediatric anaesthetist. Important indications include acute and chronic stridor, chronic obstructive airway disease, mucoviscidosis and foreign body aspiration. The best and safest techniques are outlined depending on the clinical situation, and the most frequent complications are discussed, e.g. hypoxaemia, respiratory arrest, laryngospasm, bronchial obstruction, pneumothorax and overdosing of local anaesthetic agents.

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Quality of Emergence from Anesthesia and Incidence of Vomiting with Remifentanil in a Pediatric Population

Abstract: A randomized, controlled clinical trial of 115 patients undergoing dental restoration indicated that an anesthetic technique using remifentanil provided quality of emergence comparable to and no greater incidence of vomiting than a nonopiate technique.

Cited by 10 publications

References 6 publications

Effect of Remifentanil on Postoperative Vomiting After Strabismus Surgery in Preschool Children: A Prospective Randomized Controlled Trial

Effect of Remifentanil on Postoperative Vomiting After Strabismus Surgery in Preschool Children: A Prospective Randomized Controlled Trial

Comparative evaluation of bispectral index system after sedation with midazolam and propofol combined with remifentanil versus ketamine in uncooperative during dental procedures

Anästhesiologisches Management zur Endoskopie der Atemwege bei Kindern

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