“…27 Prior systematic reviews of quality indicators use the same instrument. 28 , 29 , 30 , 31 The AIRE instrument consists of four domains (1. purpose, relevance, and organizational context, 2. stakeholder involvement, 3. scientific evidence, and 4. additional evidence, formulation, and usage) subdivided into 20 items which are listed in Supplementary Data S2. Each item is scored on a 4-point Likert scale (1 = strongly disagree or no information provided, 2 = disagree, 3 = agree, 4 = strongly agree).…”