Quality evaluation of Lycium barbarum L. fruits from different regions in China based on 2-O-β-D-glucopyranosyl-L-ascorbic acid

Zhu, Baojie; Zhang, Wanxin; Qin, You; Zhao, Jing; Li, Shaoping

doi:10.1016/j.jfca.2022.104512

Cited by 3 publications

(2 citation statements)

References 23 publications

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“…In this study, the L. barbarum samples which were collected from different regions of China, were geographically distinct. The geographical and climate factors may affect the accumulation of many metabolites of L. barbarum, 6,12,13 as well as polysaccharides. Therefore, the variances of polysaccharides or polysaccharides hydrolysate from different regions deserve further exploration especially in tracing the origins of L. barbarum.…”

Section: Content Of L Barbarum Polysaccharides and Monosaccharides In...mentioning

confidence: 99%

“…Therefore, it is important to develop methods for the effective geographical origin recognisation of L. barbarum so as to protect the benefits of consumers and farmers. So far, there had been some reports of the characterisation and geographical origin discrimination for the chemical constituents of L. barbarum, which mainly focus on micromolecules such as flavonoids, 6 anthocyanin, 11 fatty acids and phytosterols, 12 vitamin C derivative, 13 and so on. Polysaccharides are one of the most representative classes of bioactive components from L. barbarum, which have various pharmacological activities, such as immunomodulatory, 14 anticancer, 14 liver protection, 15 and antioxidant.…”

Section: Introductionmentioning

confidence: 99%

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Comparison of Lycium barbarum fruits polysaccharide from different regions of China by acidic hydrolysate fingerprinting‐based HILIC‐ELSD‐ESI‐TOF‐MS combined with chemometrics analysis

Zhao

YiXin

Yang

et al. 2022

Phytochemical Analysis

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Introduction: Lycium barbarum is an edible fruit widely used in herbal medicines and as a functional food. Polysaccharide is one of the most important active ingredients. Only L. barbarum grown in the Ningxia region of China are officially recognised as suitable for use in traditional Chinese medicine, but the systematic comparison of L. barbarum polysaccharide between Ningxia and the other growing regions of China has been rarely reported. Objective: To compare the difference of L. barbarum polysaccharide from different grown regions of China. Methods: A chemical fingerprint of L. barbarum polysaccharide hydrolysates was established based on controlled acidolysis combined with hydrophilic interaction liquid chromatography-evaporative light scattering detection-electrospray ionisationtime-of-flight-mass spectrometry (HILIC-ELSD-ESI-TOF-MS). Then, it was employed for the comparison of L. barbarum samples from different geographical origins of China combined with chemometrics analysis. Results: Six monosaccharides [rhamnose (Rha), xylose (Xyl), arabinose (Ara), mannose (Man), glucose (Glu), galactose (Gal)] were qualitatively and quantitatively determined and four glycoconjugates were preliminarily identified from the hydrolysates. Content determination for the polysaccharide and monosaccharide indicated obvious geographical features. The HILIC-ELSD fingerprint combined with partial least squares-discriminant analysis (PLS-DA) was able to differentiate L. barbarum samples from Ningxia, Xinjiang, Gansu and Qinghai regions with 89.19% classification accuracy. Orthogonal projection to latent structure discriminant analysis (OPLS-DA) was able to differentiate between samples from Ningxia and those from the other three growing regions, polysaccharide and Ara were the potential chemical markers.Conclusions: These findings form the basis of a reliable method to trace the region of origin of L. barbarum sample and thereby, improve the quality control of L. barbarum therapeutic polysaccharides.

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Section: Content Of L Barbarum Polysaccharides and Monosaccharides In...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparison of Lycium barbarum fruits polysaccharide from different regions of China by acidic hydrolysate fingerprinting‐based HILIC‐ELSD‐ESI‐TOF‐MS combined with chemometrics analysis

Zhao

YiXin

Yang

et al. 2022

Phytochemical Analysis

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In vivo absorption and excretion in rats and in vitro digestion and fermentation by the human intestinal microbiota of 2-O-β-d-glucopyranosyl-l-ascorbic acid from the fruits of Lycium barbarum L

Dong,

Peng,

et al. 2024

Food Funct.

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Investigation into Antioxidant Mechanism of Lycium barbarum Extract in Carbendazim-Induced PC12 Cell Injury Model through Transcriptomics and Metabolomics Analyses

Liu,

Chen,

Wen

et al. 2024

Foods

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Lycium barbarum L., an important functional food in China, has antioxidant and antiaging activity. However, the exact antioxidant activity mechanism of Lycium barbarum extracts (LBE) is not well understood. Therefore, a carbendazim (CBZ)-induced PC12 cell injury model was constructed and vitrificated to study the antioxidant activity of fresh LBE on the basis of extraction parameter optimization via the full factorial design of experiments (DOE) method. The results showed that the pretreatment of PC12 cells with LBE could reduce the reactive oxygen species (ROS) level by 14.6% and inhibited the mitochondrial membrane potential (MMP) decline by 12.0%. Furthermore, the integrated analysis revealed that LBE played an antioxidant role by activating oxidative phosphorylation (OXPHOS) and restoring MMP, maintaining the tricarboxylic acid (TCA) cycle stability, and regulating the GSH metabolic pathway. The results of the present study provide new ideas for the understanding of the antioxidant function of LBE from a global perspective.

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Quality evaluation of Lycium barbarum L. fruits from different regions in China based on 2-O-β-D-glucopyranosyl-L-ascorbic acid

Cited by 3 publications

References 23 publications

Comparison of Lycium barbarum fruits polysaccharide from different regions of China by acidic hydrolysate fingerprinting‐based HILIC‐ELSD‐ESI‐TOF‐MS combined with chemometrics analysis

Comparison of Lycium barbarum fruits polysaccharide from different regions of China by acidic hydrolysate fingerprinting‐based HILIC‐ELSD‐ESI‐TOF‐MS combined with chemometrics analysis

In vivo absorption and excretion in rats and in vitro digestion and fermentation by the human intestinal microbiota of 2-O-β-d-glucopyranosyl-l-ascorbic acid from the fruits of Lycium barbarum L

Investigation into Antioxidant Mechanism of Lycium barbarum Extract in Carbendazim-Induced PC12 Cell Injury Model through Transcriptomics and Metabolomics Analyses

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