Quality Control of Herbal Products in the Egyptian Market Used for Weight Management

Malak, Lourin G.; El-Helaly, Omnia; Ahmed, Amany A.

doi:10.21608/sjpms.2021.96694.1001

Cited by 3 publications

(4 citation statements)

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“…The results of liver function markers (Table 3), the albumin concentration for treatment groups T2 and T3 are significantly higher (p<0.05) www.kjhs.kiu.ac.ug https://doi.org/10.59568/KJHS-2023-3-1-01 KJHS 3(1); 2023. Page (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14) than that of the NC. The Albumin concentration for the T1 shows no significant difference with the NC (P=0.1606).…”

Section: Serum Liver Function Enzymes and Biomarkers After Treatment ...mentioning

confidence: 89%

“…Herbal plants are used for the healing and prevention of different ailments and form the foundation for discovery and synthesis of novel therapeutic drugs (5,7). About 80% of the world population including in East Africa still depends on herbal medicine (3,8,9).…”

Section: Introductionmentioning

confidence: 99%

“…www.kjhs.kiu.ac.ug https://doi.org/10.59568/KJHS-2023-3-1-01 KJHS 3(1); 2023. Page(1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14) rind extracts of Aloe vera in Wistar rats. Qualitative phytochemical composition of herbal drink (HD)…”

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confidence: 99%

“…AnthraquinonesNegative www.kjhs.kiu.ac.ug https://doi.org/10.59568/KJHS-2023-3-1-01 KJHS 3(1); 2023. Page(1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14) …”

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Phytochemicals and Toxicological Effects of Herbal Drink (Hd) on Liver and Kidney in Wistar Rats

S.,

E.,

et al. 2023

KJHS

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Herbal medicine use is on the increase worldwide and many studies have associated their use with hepatotoxicity and nephrotoxicity. Herbal drink (HD) is a commercial herbal supplement mainly used in Uganda. In this study, we evaluated the phytochemical composition, and acute and sub-chronic toxicological effects of HD on hepatorenal integrity in Wistar rats. Modified Lorke’s method was employed in the acute toxicity study. For the sub-chronic toxicity study, a total of sixteen (N= 16) Wistar rats were randomly allotted to four groups of four rats each (n=4). Normal control group, NC (normal dose equivalent of distilled water), Group T1 (half normal dose of HD), Group T2 (normally recommended dose equivalent of HD),and Group T3 (twice normal recommended dose of HD). All treatments were done by intragastric gavage for a period of twentyeight days. Phytochemical analysis of HD showed the presence of alkaloids, glycosides, tannins, phenolic compounds, flavonoids, saponins, and carbohydrates. The animals were able to tolerate a dose of up to 5000 mg/Kg. It was demonstratedthat continuous twenty-eight-day treatment with HD does not significantly (p>0.0 alter kidney and liver function parametersin Wistar rats. This observation concurs with the histopathological findings of the liver and kidney tissues which showed no remarkable histomorphological alterations. Regular intake of HD does not have any significant toxic effects on the liver and kidney in Wistar rats.

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Section: Serum Liver Function Enzymes and Biomarkers After Treatment ...mentioning

confidence: 89%

Section: Introductionmentioning

confidence: 99%

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confidence: 99%

“…AnthraquinonesNegative www.kjhs.kiu.ac.ug https://doi.org/10.59568/KJHS-2023-3-1-01 KJHS 3(1); 2023. Page(1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14) …”

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