Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria

Abstract

Substantial agreement for QC assessment was achieved with aid of the OSCAR-IB criteria. The task force has developed a website for free online training and QC certification. The criteria may prove useful for future research and trials in MS using OCT as a secondary outcome measure in a multi-centre setting.

Optical coherence tomography in acute optic neuritis: A population-based study

“…An experienced grader masked for clinical presentation checked all images for sufficient image quality in line with the OSCAR-IB criteria 18 and manually corrected segmentation in case of errors. Patients were scanned under photopic conditions with ceiling lights and without pupil dilation.…”

Bidirectional trans-synaptic axonal degeneration in the visual pathway in multiple sclerosis

“…In brief, peripapillary data were obtained using a 12° ring scan and macular data with a macular volume scan (20×20° field, 25 B-scans, see online supplementary figure S1). Scans were excluded from the analyses if they violated, validated international consensus quality control criteria (OSCAR-IB) 17 18. In order to assess retinal pathology potentially resulting in exclusion of OCT scans, the personal and medical history of visual symptoms was obtained from all patients and controls and judged in view of the clinical examination.…”

Detection of retinal blood vessel changes in multiple sclerosis with optical coherence tomography

“…Participants with MS (n = 58) and healthy controls without any history of ocular or neurologic disease (n = 13), were recruited for the study. We excluded some of the eyes (2 control, 2 MS-mild, and 5 MS-moderate) due to missing data (peripapillary OCT scan was not done), poor OCT image quality (where extensive manual correction would have been required) or centration, which may artificially decrease or increase the RNFL thickness (RNFL T ), but might also modify the diameter of blood vessels [31]. Patients with ophthalmologic or neurologic disorders (other than MS) including glaucoma, diabetic and hypertensive retinopathy, and/or a refractive error greater than 6 diopters, were excluded from the study.…”