Quality control and discrimination of angelica different processed products based on HPLC fingerprints combined chemometrics methods

Evaluation of the anti-inflammatory effects of volatile oils from processed products of Angelica sinensis radix by GC–MS-based metabolomics

“…3-n-butylphthalide, another important component of VOAS, could inhibit arachidonic acid metabolism (Lee et al, 2010). Fu et al reported that n-butylidenephthalide derived from AS decreased the secretion of IL-6 and TNF-a (Fu et al, 2011).Our previous studies showed that the content of ligustilide in J-VOAS was significantly higher than that in other kinds of VOAS, and the content of butene ester in C-VOAS was significantly higher than that in other kinds of VOAS (Guo et al, 2010). So the processing method was an important factor, which could affect the efficacy of AS.…”

Chemical composition analysis of Angelica sinensis (Oliv.) Diels and its four processed products by ultra‐high‐performance liquid chromatography coupled with quadrupole‐orbitrap mass spectrometry combining with nontargeted metabolomics

“…Compared with DG, the volatile oil components in YDG also showed a decreasing trend, but the content of some components was higher than that of JDG such as senkyunolide D, N-butylphthalide, Z-ligustilide, and angelicide. The results of Guo et al [45] also showed that the Z-ligustilide content in YDG was higher than that in JDG. Du et al [46] reported the laxative effect of volatile oil components of DG, and it is presumed that during the concoction process, the aromatic oil retained certain volatile oil components, which increased the laxative effect.…”

“…The results of Guo et al. [45] also showed that the Z ‐ligustilide content in YDG was higher than that in JDG. Du et al.…”