Qualité ovocytaire et embryonnaire et issue des cycles d’ICSI chez les patientes porteuses d’un syndrome des ovaires polykystiques (SOPK) versus normo-ovulantes

Kdous, Moez; Chaker, Anis; Zhioua, Amel; Zhioua, Fethi

doi:10.1016/j.jgyn.2008.12.001

Cited by 14 publications

(1 citation statement)

References 39 publications

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“…If the patient presents with clinical and ultrasound signs of OHSS, final oocyte maturation should be performed with a GnRH agonist and embryos should be frozen and transferred in a subsequent cycle 33 , 34 . Infertile women with PCOS may present with better general oocyte and embryo quality rates; however, the clinical pregnancy and live birth rates are similar to those observed in normo-ovulatory women without PCOS 35 .…”

Section: Introductionmentioning

confidence: 86%

Treatment of infertility in women with polycystic ovary syndrome: approach to clinical practice

Melo¹,

Ferriani²,

Navarro³

2015

Clinics

162

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Polycystic ovary syndrome represents 80% of anovulatory infertility cases. Treatment initially includes preconception guidelines, such as lifestyle changes (weight loss), folic acid therapy to prevent the risk of fetal neural tube defects and halting the consumption of tobacco and alcohol. The first-line pharmacological treatment for inducing ovulation consists of a clomiphene citrate treatment for timed intercourse. The second-line pharmacological treatment includes the administration of exogenous gonadotropins or laparoscopic ovarian surgery (ovarian drilling). Ovulation induction using clomiphene citrate or gonadotropins is effective with cumulative live birth rates of approximately 70%. Ovarian drilling should be performed when laparoscopy is indicated; this procedure is typically effective in approximately 50% of cases. Finally, a high-complexity reproduction treatment (in vitro fertilization or intracytoplasmic sperm injection) is the third-line treatment and is recommended when the previous interventions fail. This option is also the first choice in cases of bilateral tubal occlusion or semen alterations that impair the occurrence of natural pregnancy. Evidence for the routine use of metformin in infertility treatment of anovulatory women with polycystic ovary syndrome is not available. Aromatase inhibitors are promising and longer term studies are necessary to prove their safety.

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Section: Introductionmentioning

confidence: 86%