Qualitative risk characterization and management of occupational hazards: control banding (CB): a literature review and critical analysis.

Geraci, Charles L.; Lentz, Thomas J.; Niemeier, Richard W.

doi:10.26616/nioshpub2009152

Cited by 2 publications

(9 citation statements)

References 33 publications

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“…Although many uncertainties still exist, there is a high level of concern about the safety and health hazards of nanomaterials. Therefore, employers and workers must take a precautionary approach to risk management and the selection of prevention measures [1,4].…”

Section: Legislation and Standardizationmentioning

confidence: 99%

“…Due to these distinctions in properties, nanomaterials bring new and exciting possibilities to different industries and areas, such as engineering, information technology, medicine, and pharmaceuticals. However, the same characteristics that give nanomaterials their special properties can also lead to potential impacts on human health and the environment [1][2][3][4].…”

Section: Introduction 1nanomaterialsmentioning

confidence: 99%

“…The market for nanomaterials is rapidly growing and new generations of nanomaterials are being developed at a fast pace. Note that despite the numerous advantages of nanomaterials, there is still a significant amount of knowledge missing regarding their potential health risks [1,4].…”

Section: Introduction 1nanomaterialsmentioning

confidence: 99%

“…In fact, there are significant concerns regarding the health effects of nanomaterials [4]. The Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) found that there are proven health hazards associated with a number of manufactured nanomaterials.…”

Section: Introduction 1nanomaterialsmentioning

confidence: 99%

“…Workers can be exposed to nanomaterials in various work environments where nanomaterials are used, handled, or processed, which can cause them to become airborne and potentially inhaled or come into contact with the skin. This type of exposure is most common during the production stage, but workers throughout the supply chain may also come into contact with nanomaterials without realizing it [4]. This raises concerns about the lack of measures in place to prevent exposure, making it crucial to educate workers about the potential risks.…”

Section: Introduction 1nanomaterialsmentioning

confidence: 99%

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Managing Nanomaterials in the Workplace by Using the Control Banding Approach

Ramos

Almeida

2023

IJERPH

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Nanomaterials offer new technical and commercial opportunities. However, they may also pose risks to consumers and the environment and raise concerns about occupational health and safety. An overview of the standardization in the area of nanomaterials is presented. Focus is given to the standard ISO/TS 12901-2:2014, which describes the use of a control banding approach for controlling the risks associated with occupational exposures to nano-objects and their aggregates and agglomerates greater than 100 nm. The article also presents a case study on a textile finishing company that implements two chemical finishes containing nanomaterials. A risk analysis was conducted to assess the hazards associated with workers handling nanomaterials. Control banding was applied, and measures such as appropriate ventilation and use of protective equipment are proposed to mitigate risks. In some cases, additional measures, such as a closed booth and smoke extractor, are required. The safety data sheets are a primary source of information on how to handle and care for products containing nanomaterials, but the information provided is still limited in terms of the specific hazards and risks posed by nanomaterials.

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Section: Legislation and Standardizationmentioning

confidence: 99%

Section: Introduction 1nanomaterialsmentioning

confidence: 99%

Section: Introduction 1nanomaterialsmentioning

confidence: 99%

Section: Introduction 1nanomaterialsmentioning

confidence: 99%

Section: Introduction 1nanomaterialsmentioning

confidence: 99%

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Managing Nanomaterials in the Workplace by Using the Control Banding Approach

Ramos

Almeida

2023

IJERPH

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Defining Molecular Initiating Events of Airway Sensory Irritation in Support of Predictive Testing Approaches

FrankEvan

HaberLynne

Beth

et al. 2018

Applied In Vitro Toxicology

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Airway irritant exposures in the workplace cause sensory irritation symptoms or signs such as nose and throat pain, rhinorrhea, cough, and airway obstruction, and are associated with nonallergic airway hyperresponsiveness. Using toxicity data to derive chemical-specific occupational exposure limits (OELs) is a critical step in protecting worker health. Respiratory irritation is one of the most common critical effects cited in risk assessments supporting OEL values. However, toxicity data capturing airway sensory irritation responses are often not available for chemicals requiring assessment, even when occupational exposure scenarios indicate inhalation as a route of exposure. As a result, many existing OELs may be inadequately protective against airway irritant responses. This highlights a need for hazard identification methods that are economical, ethical, and informative for sensory irritation effects. In this review, existing knowledge regarding mechanisms of irritancy in the airway is integrated into a mechanistic event framework that accommodates the chemical diversity of airway irritants. This framework identifies discrete molecular initiating events and outcome modifiers upstream of sensory irritation responses. These include activation of specific receptors by irritant ligands, as well as lipid peroxidation, oxidative stress, rapid saline changes, and membrane-detergent events that initiate neuroexcitatory and inflammatory processes in airway nerves and tissues. The use of an in vitro predictive assay suite to measure these events may allow for a low-cost, medium-throughput option for screening large numbers of chemicals for sensory irritant hazards, thereby indicating data needs necessary for setting OELs.

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Qualitative risk characterization and management of occupational hazards: control banding (CB): a literature review and critical analysis.

Cited by 2 publications

References 33 publications

Managing Nanomaterials in the Workplace by Using the Control Banding Approach

Managing Nanomaterials in the Workplace by Using the Control Banding Approach

Defining Molecular Initiating Events of Airway Sensory Irritation in Support of Predictive Testing Approaches

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