Qualitative Assessment of Patient-reported Outcomes in Adults With Eosinophilic Esophagitis

Taft, Tiffany; Kern, Emily; Keefer, Laurie; Burstein, David; Hirano, Ikuo

doi:10.1097/mcg.0b013e3182166a5a

Cited by 69 publications

(78 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…No symptom is pathognomonic for EoE, and symptoms cannot be used in isolation to diagnose EoE because validated symptom metrics are still under development. 100,[286][287][288][289] Typical endoscopic features include pallor, furrows, rings, exudates, narrowing, and strictures, but endoscopic features in the absence of biopsy should not be used to diagnose EoE. 100,290 Subjects with suspected EoE should be treated with high-dose PPIs to rule out acid-induced esophageal infiltration of eosinophils.…”

Section: Section V: Adverse Reactions To Food Additivesmentioning

confidence: 99%

Food allergy: A practice parameter update—2014

Bernstein¹,

Blessing-Moore²,

Khan³

et al. 2014

Journal of Allergy and Clinical Immunology

706

564

View full text Add to dashboard Cite

Section: Section V: Adverse Reactions To Food Additivesmentioning

confidence: 99%

Food allergy: A practice parameter update—2014

Bernstein¹,

Blessing-Moore²,

Khan³

et al. 2014

Journal of Allergy and Clinical Immunology

706

564

View full text Add to dashboard Cite

“…The more general SF-36 questionnaire has only been used by one other research team for an EoE study [30]. Taft et al showed using qualitative interviews that patients with EoE have concerns about impact of eating, dysphagia episodes and available treatments among other things but Eur Arch Otorhinolaryngol also that they felt a relief upon receiving diagnosis [31]. The same authors have also developed a recent adult EoE quality of life questionnaire [32].…”

Section: Discussionmentioning

confidence: 97%

Dysphagia and health-related quality of life in patients with eosinophilic esophagitis: a long-term follow-up

Larsson

Bergman

Finizia

et al. 2015

Eur Arch Otorhinolaryngol

View full text Add to dashboard Cite

Eosinophilic esophagitis (EoE) is a chronic immune/antigen-mediated disease, with dysphagia as the main symptom. The aim of this study was to survey symptoms and health-related quality of life in adult patients with EoE at least 1 year after diagnosis and a 2-month course of topical corticosteroids. Forty-seven consecutive patients [79 % males, mean age 49 years (range 18-90 years)] were evaluated using three different questionnaires at three different occasions: the Watson Dysphagia Scale (WDS), the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Oesophageal Module 18 (EORTC QLQ-OES18) and the Short Form-36 (SF-36). The median time from diagnosis to the long-term follow-up was 23 months (range 12-34 months). The WDS scores and the EORTC QLQ-OES18 Dysphagia and Eating scale scores were improved after 2 months of treatment (p = 0.00007, p = 0.01, p = 0.004, respectively), as were the long-term follow-up scores (p = 0.01, p = 0.03, p = 0.005, respectively), relative to the scores at diagnosis. In addition, the EORTC QLQ-OES18 Choking scores were improved after the steroid course (p = 0.003) but not after the long-term follow-up. No significant differences were detected with respect to the SF-36 scores. In summary, EoE seems to be associated with a substantial burden of symptoms that improve significantly after treatment. A partial remission persists more than 1 year after diagnosis and the discontinuation of medication. The WDS and the EORTC QLQ-OES18 appear to be sensitive instruments appropriate for surveillance in these patients.

show abstract

“…The aforementioned qualities of EGIDs, associated symptom burden, and limited treatment options can impact several psychosocial aspects within a patients’ health-related quality of life (HRQOL) 6, 7 . Patients with an EGID have reported an interference in social relationships and interactions, such as experiencing worry about eating in restaurants, scaring others, and hiding choking from others 6, 7 .…”

Section: Introductionmentioning

confidence: 99%

Stigma perceptions in patients with eosinophilic gastrointestinal disorders

Guadagnoli

Taft

Keefer

2017

Diseases of the Esophagus

View full text Add to dashboard Cite

This study aims to evaluate the presence of perceived stigma in people diagnosed (self-reported) with an eosinophilic gastrointestinal disorder and examine the relationship to the patient’s health related quality of life and additional psychosocial patient-reported outcomes. 149 patients diagnosed for a minimum of 6 months participated in the study. Eligible participants completed questionnaires to assess perceived stigma, psychological functioning, and health related quality of life. Perceived stigma was moderately associated with a decrease in total health related quality of life and perceived treatment efficacy. Additionally, greater perceived stigma was positively correlated with an increase in anxiety, depression, and healthcare utilization. The study demonstrates the influence of perceived stigma on several aspects of health related quality of life in patients with these illnesses. As such, it is important for health professionals to be aware of stigma in patients diagnosed with an eosinophilic gastrointestinal disorder.

show abstract

Qualitative Assessment of Patient-reported Outcomes in Adults With Eosinophilic Esophagitis

Cited by 69 publications

References 0 publications

Food allergy: A practice parameter update—2014

Food allergy: A practice parameter update—2014

Dysphagia and health-related quality of life in patients with eosinophilic esophagitis: a long-term follow-up

Stigma perceptions in patients with eosinophilic gastrointestinal disorders

Contact Info

Product

Resources

About