Qualitative and Quantitative Assessment of Taste and Smell Changes in Patients Undergoing Chemotherapy for Breast Cancer or Gynecologic Malignancies

Steinbach, Silke; Hummel, Thomas; Böhner, Christina; Berktold, Sabina; Hundt, Walter; Kriner, Monika; Heinrich, P; Sommer, H; Hanusch, Claus; Prechtl, A.; Schmidt, B.F.; Bauerfeind, Ingo; Seck, Katharina; Jacobs, Volker R.; Schmalfeldt, Barbara; Harbeck, Nadia

doi:10.1200/jco.2008.19.2690

Cited by 203 publications

(170 citation statements)

References 29 publications

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“…Results from Steinbach et al [22] strongly suggest that CT agents differ from each other in their impact on TAs, but there is yet no solid evidence for this hypothesis. The survey methodology presented in this paper enabled us to reach a sample of patients receiving a wide range of commonly used CT regimens.…”

Section: Discussionmentioning

confidence: 99%

Taste Alterations in Cancer Patients Receiving Chemotherapy: A Neglected Side Effect?

et al. 2010

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After completing this course, the reader will be able to:1. Evaluate the effect of various chemotherapy regimens on taste alterations.2. Investigate the effect of chemotherapy-induced taste alterations on patients and use available dietary approaches such as taste enhancement and substitution of proteins and nutrients of avoided food to improve quality of life.This article is available for continuing medical education credit at CME.TheOncologist.com. CME CME ABSTRACTBackground. Taste alterations (TAs) are a frequent but under-recognized treatment side effect in cancer pa-

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Section: Discussionmentioning

confidence: 99%

Taste Alterations in Cancer Patients Receiving Chemotherapy: A Neglected Side Effect?

et al. 2010

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“…[11] Yiyeceklere yönelik olarak; besinlere daha fazla tatlandırıcı konabilir. Etler tatlı sıvılarda bekletilebilir.…”

Section: Discussionunclassified

Chemoterapy induced taste and smell changes in pediatric cancer patients

Karaman¹

2013

TJ Oncol

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OBJECTIVESWe aimed to find the rate and the properties of chemotherapy induced taste and smell changes in pediatric cancer patients. METHODSOur study group consisted of 66 pediatric cancer patients whose families accepted to participate. They were asked a 18-item-questionnaire. RESULTSTaste and smell changes were detected in 56 patients (84%) and 61 patients (92%) respectively with no difference in boys and girls. The rate of taste changes of patients ≤10 years old was 72% whereas for the older patients, this rate was 91%. The most frequent complaint was bitter taste change in all age groups. There was no difference between their chemotherapy regimens. CONCLUSIONIt was shown that changes in taste and smell in children were as frequent as in adults. It was ignored by most of the patients but some of them were trying to take some corrective measures.Key words: Children; cancer; chemotherap; smell; taste. AMAÇBu çalışma, kemoterapi tedavisi uygulanan pediatrik hastalarda tat ve koku değişikliklerinin sıklığı ve özelliklerini araştır-mak amacıyla yapıldı. GEREÇ VE YÖNTEMPediatrik onkoloji kliniğinde yatarak kemoterapi alan ve araş-tırmayı kabul eden 66 çocuk hastada tat ve koku değişiklikleri, 18 soruluk bir anketle sorgulandı. BULGULARÇalışmada 56 (%84) hastada tat, 61 (%92) hastada ise koku değişikliği saptandı, cinsiyet farkı bulunmadı. Yaş gruplarına göre değerlendirildiğinde 10 yaş ve altındaki hastalarda tat değişikliği %72 olarak saptanırken 10 yaş üzeri hasta grubunda bu sıklık %91 olarak bulundu ve fark anlamlı idi. Her iki yaş grubundaki hastalar en sık acı tat değişikliğinden (%39 ve %41) yakındı. Kemoterapi protokollerine göre de tat ve koku değişikliklerinde anlamlı farklılık saptanmadı. SONUÇBizim çalışmamızda, erişkinlerde olduğu gibi çocuklarda da sıklıkla tat ve koku değişikliklerinin geliştiği, hastaların ya bunu göz ardı ettiği, ya da düzeltici önlemler almaya çalıştığı izlenmiştir.Anahtar sözcükler: Çocuk; kanser; kemoterapi; koku; tat. yılında ECCO-ESMO Kongresi Berlin'de daha 44 hasta ile önsonuçları poster olarak sunulmuştur.İlaçlara bağlı tat ve koku değişiklikleri bilinenden çok daha sık rastlanır. Bu durum özellikle onkoloji hastalarında daha belirgindir. Tat ve koku değişikliklerinin sıklığını değerlendirmek oldukça zor, ölçülebilir kayıp ise nadirdir. [1] Bunun nedeni, tat reseptörlerinin geniş bir alana yayılması, birden çok kraniyal sinir ile ilgili ve "kemosensör" sistemin (kimyasal algılama) çok karmaşık olmasıdır. Bütün bu sebeplerle oluşan odaksal kayıplar hastalar tarafından fark edilmeyebilirler. Hormonal etkilerin en yoğun yaşandığı dönemler olan adet dönemi ve gebelikte de artmış koku hassasiyeti yaşanabilir. [2]

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“…Smell and taste disturbances are very often symptoms of nasal polyposis [2]. It has been found that, olfactory and gustatory functions significantly decrease during chemotherapy and recover almost completely 3 months after chemotherapy [3].…”

Section: Discussionmentioning

confidence: 99%

Qualitative and Quantitative Representation of Taste Disturbances: How We Do It by Pentagon Chart

Naik

Cf²

2010

Indian J Otolaryngol Head Neck Surg

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Taste is a chemical sense responding to chemical stimuli. In our daily practice as ENT practitioners or Neurologists we do come across patients complaining of taste disturbances. Tests for taste have to be performed regularly in the clinical centres as well as in neurological labs as a part of complete work up for neurotology cases. Assessment of taste sensation can be easily done in a neurological clinic by chemogustometry as described by Claussen. The stimuli used are chemicals, representative substances for the four qualities of sweet, salty, sour and bitter, in graded solutions. These semi-quantitative results are plotted on a pentagon scheme devised by Claussen. The points of the best results for glucose, sodium chloride, citric acid, phenylthio-urea and quinine then are connected with a coloured line. That gives a linked graphic structure, which can be read by the physician at one glance. Different patterns are obtained for normal taste, taste-blindness for phenylthio-urea, ageusia, partial ageusias for glucose, or sodium chloride or citric acid or quinine or their combinations and parageusias. In this article we present different patterns of taste disturbances depicted on the pentagon chart highlighting the easy interpretation of chemogustometry.

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Qualitative and Quantitative Assessment of Taste and Smell Changes in Patients Undergoing Chemotherapy for Breast Cancer or Gynecologic Malignancies

Cited by 203 publications

References 29 publications

Taste Alterations in Cancer Patients Receiving Chemotherapy: A Neglected Side Effect?

Taste Alterations in Cancer Patients Receiving Chemotherapy: A Neglected Side Effect?

Chemoterapy induced taste and smell changes in pediatric cancer patients

Qualitative and Quantitative Representation of Taste Disturbances: How We Do It by Pentagon Chart

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