2021
DOI: 10.1109/access.2021.3116980
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Qualitative and Quantitative Analysis of Caffeine in Medicines by Terahertz Spectroscopy Using Machine Learning Method

Abstract: Caffeine is an alkaloid and may be the most commonly ingested pharmacologically active substance in the world, but continuous abuse may lead to "caffeine poisoning". In this study, we propose a method for the qualitative and quantitative analysis of caffeine in various medicines using terahertz spectroscopy combined with chemometrics. By comparing this terahertz (THz) spectroscopy technology (Fourier transform infrared instrument, FTIR) with high performance liquid chromatography (HPLC) and Raman spectroscopy,… Show more

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Cited by 6 publications
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“…Terahertz (THz) radiations [7], located between radio waves and infrared light, are electromagnetic waves ranging from 0.1 to 10 THz. The most important use of THz radiation was in the development of THz spectroscopy which has evolved into a tool of tremendous applications due to the development of modern ultrafast optics [8,9]. Terahertz imaging technology has unique advantages in both spectrum and imaging, containing a large amount of image and spectral information.…”
Section: Introductionmentioning
confidence: 99%
“…Terahertz (THz) radiations [7], located between radio waves and infrared light, are electromagnetic waves ranging from 0.1 to 10 THz. The most important use of THz radiation was in the development of THz spectroscopy which has evolved into a tool of tremendous applications due to the development of modern ultrafast optics [8,9]. Terahertz imaging technology has unique advantages in both spectrum and imaging, containing a large amount of image and spectral information.…”
Section: Introductionmentioning
confidence: 99%