Quadrupia: Derivation of G-quadruplexes for organismal genomes across the tree of life
Nikol Chantzi,
Akshatha Nayak,
Fotis A. Baltoumas
et al.
Abstract:G-quadruplex DNA structures exhibit a profound influence on essential biological processes, including transcription, replication, telomere maintenance, and genomic stability. These structures have demonstrably shaped organismal evolution. However, a comprehensive, organism-wide G-quadruplex map encompassing the diversity of life has remained elusive. Here, we introduce Quadrupia, the most extensive and well-characterized G-quadruplex database to date, facilitating the exploration of G-quadruplex structures acr… Show more
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