Quadricuspid aortic valve infective endocarditis

Jackson, Christopher; Sarwar, Tahira; Hwang, Inyong; Joglekar, Kiran; Alsafwah, Shadwan

doi:10.1002/jcu.22495

Cited by 6 publications

(6 citation statements)

References 10 publications

(31 reference statements)

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“…Transesophageal echocardiography is the preferred tool to define valve morphology, valve function, and coronary ostial displacement. Jackson and colleagues 6 reported a higher incidence of IE in QAV compared to any other aortic valve morphology (1.5% in bicuspid patients, 9% in quadricuspid patients), explained by the fact that unequal cusps may lead to uneven distribution of valvular stress and flow disturbance, leading to endothelial damage facilitating bacterial implants. 2…”

Section: Discussionmentioning

confidence: 99%

Infective endocarditis of a native quadricuspid aortic valve

Ascaso

Pruna-Guillen

Hernández‐Meneses

et al. 2021

Asian Cardiovasc Thorac Ann

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Quadricuspid aortic valve complicated with infective endocarditis is an uncommon clinical scenario. The indications for surgery and medical management do not differ from other types of aortic valve endocarditis. Commonly present structural abnormalities pose an increased risk of complete heart block and coronary occlusion during valve replacement. We present a case of quadricuspid aortic valve complicated with infective endocarditis, with surgical images of the valve.

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Section: Discussionmentioning

confidence: 99%

Infective endocarditis of a native quadricuspid aortic valve

Ascaso

Pruna-Guillen

Hernández‐Meneses

et al. 2021

Asian Cardiovasc Thorac Ann

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“…18 Other associated anomalies are rare and includes coronary artery anomalies, 9 non-obstructive cardiomyopathy, fibromuscular sub-aortic stenosis, 7 rupture sinus of Valsalva, [19][20][21] atrial septal defect, 11,22 partial anomalous pulmonary venous connection, 23 ventricular septal defect, 24 transposition of great arteries, 25 tetralogy of Fallot, 26,27 pulmonary valve stenosis, and congenital complete heart block. Infective endocarditis is also a potential complication 7,11,28 with reported incidence of 1.4%. 6 We are reporting a case of young girl with a quadricuspid aortic valve with mild aortic valve regurgitation, large patent ductus arteriosus, and volume-loaded left heart who had a successful device closure of her patent ductus arteriosus.…”

Section: Discussionmentioning

confidence: 99%

Quadricuspid aortic valve and a large patent ductus arteriosus treated with device closure

2021

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Quadricuspid aortic valve is a remarkably rare congenital cardiac anomaly that predominantly becomes regurgitant with the passage of time. Aortic valve stenosis and aortic root dilatation are less common in quadricuspid aortic valve as compared to bicuspid aortic valve. The clinical presentation depends upon the functional status of the aortic valve, left ventricular function, and associated cardiac or coronary anomalies. The quadricuspid aortic valve is easily visualised during transthoracic echocardiogram with a characteristic X pattern of aortic valve in diastole. The association of quadricuspid aortic valve with patent ductus arteriosus is exceedingly rare. We are reporting a case of young girl with mildly regurgitant quadricuspid aortic valve, large patent ductus arteriosus, and volume-loaded left heart who underwent a successful device closure of her patent ductus arteriosus. To the best of our knowledge, such a case is being reported from Pakistan for the first time.

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“…We could not find any reports of increased incidence of infective endocarditis in QAV. However, QAV endocarditis has increased risk for complications such as progressive AR, decompensated heart failure, and valve perforation [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

“…The quadricuspid aortic valve (QAV) is a rare congenital anomaly with an incidence of 0.008 to 0.043% [ 3 ]. Few cases of endocarditis in QAV have been reported [ 4 ]. We report a patient presenting with endocarditis of previously undiagnosed QAV, soon after recovering from dengue fever.…”

Section: Introductionmentioning

confidence: 99%

Staphylococcal endocarditis in a quadricuspid aortic valve following uncomplicated dengue infection: a case report

et al. 2020

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Background Dengue fever is endemic and a leading health problem in Sri Lanka. Increased incidence of concurrent bacteremia in patients with dengue infection is a recognized complication. However, Staphylococcal endocarditis following dengue fever is uncommon. Quadricuspid aortic valve (QAV) is a rare congenital anomaly and few cases of infective endocarditis have been reported in QAV. Case presentation A 32-year-old Sri Lankan male presented to the National Hospital of Sri Lanka with recurrence of fever and acute left hemiplegia following an uncomplicated recovery of dengue fever. He was diagnosed to have Staphylococcal infective endocarditis of quadricuspid aortic valve, with septic emboli to brain and spleen. He was managed with intravenous vancomycin initially, however, due to inadequate response, intravenous linezolid was added. He developed rhabdomyolysis with very high creatine phosphokinase leading to acute kidney injury, which settled with the cessation of linezolid. The patient succumbed to his illness despite aggressive antimicrobial therapy and maximum supportive care while being assessed for aortic valve replacement. Conclusions This case illustrates three clinical issues that a clinician should be aware of. Firstly, the possibility of a serious secondary bacterial infection as a cause for recurrence of fever following dengue infection. Secondly, this case highlights the importance of identifying QAV as a cause for complicated infective endocarditis of increased severity. The report also denotes the value of being vigilant of linezolid induced rhabdomyolysis which had a causal relationship with the commencement of the drug and its cessation.

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Quadricuspid aortic valve infective endocarditis

Cited by 6 publications

References 10 publications

Infective endocarditis of a native quadricuspid aortic valve

Infective endocarditis of a native quadricuspid aortic valve

Quadricuspid aortic valve and a large patent ductus arteriosus treated with device closure

Staphylococcal endocarditis in a quadricuspid aortic valve following uncomplicated dengue infection: a case report

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