QT dynamics in risk stratification after myocardial infarction

Jensen, Berit T.; Abildstrøm, Steen Zabell; Larroudé, Charlotte Ellen; Agner, E; Torp‐Pedersen, Christian; Nyvad, Ole; Ottesen, Michael; Wachtell, Kristian; Kanters, Jørgen K.

doi:10.1016/j.hrthm.2004.12.028

Cited by 51 publications

(33 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previous reports have shown that a prolonged QTc objectified in the setting of ACS correlates with its short-and long-term outcomes [2,[5][6][7]34] . Also, a prolongation of the QTc interval during the STS is a sensitive marker for myocardial ischaemia in males [35].…”

Section: Qt Interval and Acute Myocardial Ischaemiamentioning

confidence: 99%

Relationship between the QTc interval at hospital admission and the severity of the underlying ischaemia in low and intermediate risk people studied for acute chest pain

Jiménez‐Candil

Diego

González

et al. 2008

International Journal of Cardiology

View full text Add to dashboard Cite

Section: Qt Interval and Acute Myocardial Ischaemiamentioning

confidence: 99%

Relationship between the QTc interval at hospital admission and the severity of the underlying ischaemia in low and intermediate risk people studied for acute chest pain

Jiménez‐Candil

Diego

González

et al. 2008

International Journal of Cardiology

View full text Add to dashboard Cite

“…They are largely utilized to identify patients with an increased dysrhythmic risk [16,17]. At present, no study is available on QT parameters in IBD patients free of overt cardiac involvement.…”

Section: Introductionmentioning

confidence: 99%

A study on QT interval in patients affected with inflammatory bowel disease without cardiac involvement

et al. 2010

View full text Add to dashboard Cite

Cardiac involvement has been studied quite extensively in patients affected by inflammatory bowel disease but, as of now, there is no data regarding QT alterations which are well known to be linked to the risk of dangerous arrhythmias. In this study, QT parameters were digitally measured on standard 12-lead ECG in a population of 20 patients affected by inflammatory bowel disease (IBD), with no prior (recent or old) history of cardiac disease and no evidence of electrolyte imbalance. Eighteen healthy subjects formed the control group. The results obtained using non-parametric statistics (Wilcoxon-Mann-Whitney test) showed that heart rate corrected QT interval (QTc) and QTc dispersion (QTc d) values were both significantly higher in IBD patients than in the control group. QTc rank sum values in patients affected by inflammatory bowel disease were 469 versus 311 in healthy subjects (Z = 1.939, p = 0.0263). QTc d rank sum values were 460 in IBD patients versus 320 in controls (Z = 1.686 with p = 0.0459). Regardless of the cause of these QT alterations, it appears evident that accurate monitoring of QT parameters is required in these patients who often experience electrolyte disturbances and who may, in some cases, be undergoing treatment with potentially cardiotoxic drugs such as infliximab.

show abstract

“…Visible beat-to-beat alterations in cardiac repolarization, or T-wave alternans (TWA), have been reported in patients with ischemia, inherited primary electrical disorders, and electrolyte imbalances (4 -6). The presence of lower-amplitude TWA also has been independently associated with an increased risk of serious outcomes (7)(8)(9)(10)(11). Multiple approaches of assessing TWA have been described (12) but 2 methods, the spectral (8,10,(13)(14)(15)(16) and the modified moving average (MMA) methods (1,11,17,18), have been best studied.…”

Section: Discussionmentioning

confidence: 99%

Post-Exercise Assessment of Cardiac Repolarization Alternans in Patients With Coronary Artery Disease Using the Modified Moving Average Method

Slawnych

Nieminen

Kähönen

et al. 2009

Journal of the American College of Cardiology

View full text Add to dashboard Cite

Post-exercise assessment of TWA using the MMA method is a strong, independent predictor of risk in patients with CAD. The 20-microV cutpoint (87% sensitivity) appears to be most suitable in higher-risk patients, whereas the 60-microV cutpoint (95% specificity) appears more appropriate when TWA is used as a single screening test in those at lower risk. (Assessment of Noninvasive Methods to Identify Patients at Risk of Serious Arrhythmias After a Heart Attack; NCT00399503).

show abstract

QT dynamics in risk stratification after myocardial infarction

Cited by 51 publications

References 32 publications

Relationship between the QTc interval at hospital admission and the severity of the underlying ischaemia in low and intermediate risk people studied for acute chest pain

Relationship between the QTc interval at hospital admission and the severity of the underlying ischaemia in low and intermediate risk people studied for acute chest pain

A study on QT interval in patients affected with inflammatory bowel disease without cardiac involvement

Post-Exercise Assessment of Cardiac Repolarization Alternans in Patients With Coronary Artery Disease Using the Modified Moving Average Method

Contact Info

Product

Resources

About