QSRR: Quantitative Structure‐(Chromatographic) Retention Relationships

Abstract

Analytical chemistry Z 0400 QSRR: Quantitative Structure-(Chromatographic) Retention Relationships -[371 refs.]. -(KALISZAN, R.; Chem. Rev. (Washington, D. C.) 107 (2007) 7, 3212-3246; Dep. Biopharm. Pharmacodyn., Med. Acad. Gdansk, PL-80-952 Gdansk, Pol.; Eng.) -Lindner 40-280

Multiple Linear Regression: An Overview with Analytical and Physico-Chemical Applications

“…MLR was first applied [63][64][65][66][67][68][69] in the field of medicinal and pharmaceutical chemistry in order to study QSAR, and in correlation analysis of organic reactivity, i.e. prediction of n-octanol water from structures, some interesting monographs being published on this respect [65][66][67][68][69], and an in the search of solute-solvent interactions of various kinds [63].…”

“…prediction of n-octanol water from structures, some interesting monographs being published on this respect [65][66][67][68][69], and an in the search of solute-solvent interactions of various kinds [63]. A survey of selected (mainly) analytical and physico-chemical applications of MLR is given in Table 1.…”

Quantitative Structure–Retention Relationship Study of Some 5-Substituted-5-Phenylhydantoins

“…The same basic molecular properties (hydrophobic, electronic and steric) affect not only transport processes and drug-biological target interactions, but also compound retention in a chromatographic system under specific experimental conditions. Consequently, chromatography can be used as powerful techniques for estimating physicochemical parameters and biological activities [8][9][10][11][12]. Besides, chromatographic processes are dynamic that permit the strict control of experimental conditions and therefore very reproducible retention data can be obtained.…”

Quantitative Structure–Retention Relationship (QSRR) Study for Predicting Gas Chromatographic Retention Times for Some Stationary Phases

“…Quantitative Structure -Retention Relationships (QSRR) developed by Kaliszan [3] have been employed to elucidate molecular mechanism of separation in individual High Performance Liquid Chromatography (HPLC) and Thin Layer Chromatography (TLC) models or to characterize the SPs for HPLC.…”