QRS complex duration and dipyridamole gated SPECT findings in the left bundle branch block

İnanır, Sabahat; Çalışkan, Billur; Tokay, Sena; Oktay, Ahmet

doi:10.1007/s12149-008-0163-y

Cited by 1 publication

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“… 25 Such a relationship could not be found in our study. In contrast, a study by Inanir et al 26 found a correlation between minimum QRS duration and severity of MPS perfusion abnormalities in patients with LBBB. They also chose to evaluate the maximum and mean QRS durations and they found no correlation between mean QRS duration, consistent with our study, or maximum QRS duration and uptake defects on MPS images.…”

Section: Discussionmentioning

confidence: 71%

To what extent are perfusion defects seen by myocardial perfusion SPECT in patients with left bundle branch block related to myocardial infarction, ECG characteristics, and myocardial wall motion?

Hedeer

Ostenfeld

Hedén

et al. 2021

Journal of Nuclear Cardiology

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Introduction We investigated if uptake pattern on myocardial perfusion SPECT (MPS) in patients with left bundle branch block (LBBB) is related to myocardial fibrosis, myocardial wall motion, and electrocardiography (ECG) characteristics. Methods Twenty-three patients (9 women) with LBBB, examined with MPS and cardiac magnetic resonance (CMR), were included. Tracer uptake on MPS was classified by visual interpretation as typical LBBB pattern (Defect+, n = 13) or not (Defect−, n = 10) and quantitatively. CMR images were evaluated for wall thickness and for myocardial wall motion both by visual assessment and by regional myocardial radial strain from feature tracking, and for presence and location of myocardial fibrosis. ECGs were analyzed regarding QRS duration and the presence of strict criteria for LBBB. Results Wall thickness was slightly lower in the septum compared to the lateral wall in Defect+ patients (5.6 ± 1.1 vs 6.0 ± 1.3 mm, P = 0.03) but not in Defect− patients (5.6 ± 1.0 vs 5.6 ± 0.9 mm, P = 0.84). Defect+ patients showed a larger proportion of dyskinetic segments in the septum and hyperkinetic segments in the lateral wall compared to Defect− patients (P = 0.006 and P = 0.004, respectively). Decreased myocardial radial strain was associated with decreased tracer uptake by MPS (R = 0.37, P < 0.001). Areas of fibrosis did not match areas with uptake defect on MPS. No differences in ECG variables were seen. Conclusion The heterogeneous regional tracer uptake in some patients with LBBB is related to underlying regional myocardial dyskinesia, wall thickening, and wall thickness rather than stress-induced ischemia, myocardial fibrosis, or specific ECG characteristics.

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Section: Discussionmentioning

confidence: 71%