Qingqianliusus A-N, 3,4-seco-dammarane triterpenoids from the leaves of Cyclocarya paliurus and their biological activities

Chen, Zhuliang; Wu, Qian; Wu, Jia; Yang, Yong; Yang, Yu-Pei; Xie, Qiankun; Liu, Leping; Wang, Bin; Qiu, Yixing; Yu, Huang-He; Sheng, Wen‐Bing; Jian, Yuqing; Wang, Wei

doi:10.1016/j.arabjc.2022.104441

Cited by 2 publications

(1 citation statement)

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“…It is also called "Qing-qian-liu" or "Yaoqian-shu" because its fruit cluster is seen as a string of old Chinese copper coins [1][2][3]. Various bioactive constituents are found in the leaves of C. paliurus, including flavonoids, triterpenes, polysaccharides, and steroids, which have been shown to have pharmaceutical bioactivities [4][5][6]. Triterpenes, among the most important secondary metabolites in C. paliurus, attract much attention for their anti-diabetic, anti-inflammatory, and anti-cancer medicinal values [7,8].…”

Section: Introductionmentioning

confidence: 99%

Effects on the Synthesis and Accumulation of Triterpenes in Leaves of Cyclocarya paliurus under MeJA Treatment

Xia,

Wang,

Chen

et al. 2023

Forests

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Cyclocarya paliurus (Batal.) lljinskaja, the sole and multi-functional tree species of the family Juglandaceae, grows extensively in subtropical areas of China. Species-specific triterpenoids in its leaves have validated health-promoting effects, including hypoglycemic and hypolipidemic activities. To illustrate the effect of MeJA treatment on the accumulation and biosynthesis of triterpenoids in C. paliurus leaves at different stages of maturity, the contents of total triterpenoids and six triterpene compounds, along with the relative expression of three key genes, were detected. The results showed that the contents of triterpenes and expression patterns of the genes significantly differed among the samples. Different treatment times also had diverse effects on triterpenoid accumulation and gene expression. MeJA treatment had positive effects on total triterpenoids, cyclocaric acid B, and cyclocarioside A/B, especially in young leaves. Gene expression was highest in young leaves after 10 days of treatment, indicating that they were the most sensitive to MeJA. This study provided a reference for improving the accumulation of triterpenoids in C. paliurus plantations in the future.

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