Q Fever Cluster Among Raw Milk Drinkers in Michigan, 2011

Signs, Kimberly; Stobierski, Mary Grace; Gandhi, Tejal

doi:10.1093/cid/cis690

Cited by 65 publications

(56 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[2][3][4][5][6][7][8][9] Inhalation of infectious organisms is widely recognized as the most prevalent route of exposure; transmission by ingestion of unpasteurized milk, tick bite, sexual contact, and transfusion of infected blood products have rarely been implicated in rare human infections. [10][11][12][13][14] Large outbreaks associated with inhalational exposure have occurred in slaughterhouses, auction yards, dairies, military units, laboratories, and households. [15][16][17][18][19][20][21] In humans in the United States, acute Q fever most commonly presents as a flu-like illness, more rarely as hepatitis or pneumonia; asymptomatic infections have also been documented.…”

Section: Introductionmentioning

confidence: 99%

Q Fever in the United States: Summary of Case Reports from Two National Surveillance Systems, 2000–2012

Dahlgren

McQuiston

Massung

et al. 2015

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Abstract. Q fever is a worldwide zoonosis historically associated with exposure to infected livestock. This study summarizes cases of Q fever, a notifiable disease in the United States, reported to the Centers for Disease Control and Prevention through two national surveillance systems with onset during 2000-2012. The overall incidence rate during this time was 0.38 cases per million persons per year. The reported case fatality rate was 2.0%, and the reported hospitalization rate was 62%. Most cases (61%) did not report exposure to cattle, goats, or sheep, suggesting that clinicians should consider Q fever even in the absence of livestock exposure. The prevalence of drinking raw milk among reported cases of Q fever (8.4%) was more than twice the national prevalence for the practice. Passive surveillance systems for Q fever are likely impacted by underreporting and underdiagnosis because of the nonspecific presentation of Q fever.

show abstract

Section: Introductionmentioning

confidence: 99%

Q Fever in the United States: Summary of Case Reports from Two National Surveillance Systems, 2000–2012

Dahlgren

McQuiston

Massung

et al. 2015

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

show abstract

“…Zoonotic Q fever in humans has generally been linked with transitory outbreaks of the disease in animals [2,3]. Humans are primarily infected through inhalation of C. burnetii in aerosols, resulting from occupational exposures, although transmissions through oral ingestion of contaminated food are documented [4,5]. While infected ruminants remain largely asymptomatic, the primary signs of C. burnetii include spontaneous, late-term abortions in pregnant animals.…”

Section: Resultsmentioning

confidence: 99%

Low seroprevalence of Coxiella burnetii in Boer goats in Missouri

Baker

Pithua

2014

BMC Res Notes

View full text Add to dashboard Cite

BackgroundGoats are known reservoirs of Coxiella burnetii, the etiologic agent of Q fever. However, there has been very little research on the prevalence of C. burnetii exposure and risk in meat goats farmed in the US. Banked serum samples were secondarily tested for C. burnetii specific antibodies.FindingsThe animal and herd-level seroprevalence estimates for C. burnetii were 1.2% (3/249) and 4.2% (1/24) respectively. Within-herd seroprevalence ranged from 0% to 1.2%.ConclusionsThis study indicates that seroprevalence of C. burnetii in Boer goats raised in Missouri was low, but it does not preclude the existence of a higher level of infection in Missouri’s meat goat herds. This result is inconclusive because this study was disadvantaged by the small number of individual animal and herds tested, which compromised the statistical power of this study to detect a possible higher seroprevalence of C. burnetii in this population, if present. More research is warranted to corroborate the preliminary findings reported here in order to determine the public health significance C. burnetii infection risks associated with contemporary goat production systems in the US.

show abstract

“…La consommation de lait cru infecté par C. burnetii, bien qu'elle provoque des séroconversions, n'a jamais été clairement associée à une maladie clinique chez l'humain (Benson et al 1963;Krumbiegel et Wisniewski 1970;Angelakis et Raoult 2010). Une publication récente suggère une transmission par les produits laitiers, mais l'investigation décrite ne permet pas d'exclure avec certitude une transmission aérienne (Signs et al 2012). L'analyse de produits laitiers en France a démontré la présence de l'ADN de C. burnetii mais pas de bactéries viables (Eldin et al 2013).…”

Section: Mode De Contaminationunclassified

Coxiella burnetii, agent de la fièvre Q

Boarbi¹,

Frétin²,

Mori³

2016

Can. J. Microbiol.

View full text Add to dashboard Cite

Résumé : La fièvre Q est une zoonose de répartition mondiale excepté la Nouvelle-Zélande. Elle est due à une bactérie intracellulaire : Coxiella burnetii. Cette infection passe souvent inaperçue car la manifestation principale de la forme aiguë de la maladie est un syndrome pseudogrippal spontanément résolutif. C'est l'épidémie qui a eu lieu aux Pays-Bas qui a attiré l'attention sur cette maladie qui était moins étudiée auparavant. Cette synthèse résume la description de la bactérie (taxonomie, cycle intracellulaire et génomique) mais également la maladie (description, diagnostic, pathogénie et épidémiologie). Enfin, la vaccination de l'humain et des animaux est également analysée. Mots-clés : Coxiella burnetii, fièvre Q, épidémiologie, description, génomique.Abstract: Q fever is a zoonosis of worldwide distribution with the exception of New Zealand. It is caused by an intracellular bacterium, Coxiella burnetii. The disease often goes underdiagnosed because the main manifestation of its acute form is a general self-limiting flu-like syndrome. The Dutch epidemics renewed attention to this disease, which was less considered before. This review summarizes the description of C. burnetii (taxonomy, intracellular cycle, and genome) and Q fever disease (description, diagnosis, epidemiology, and pathogenesis). Finally, vaccination in humans and animals is also considered.

show abstract

Q Fever Cluster Among Raw Milk Drinkers in Michigan, 2011

Cited by 65 publications

References 12 publications

Q Fever in the United States: Summary of Case Reports from Two National Surveillance Systems, 2000–2012

Q Fever in the United States: Summary of Case Reports from Two National Surveillance Systems, 2000–2012

Low seroprevalence of Coxiella burnetii in Boer goats in Missouri

Coxiella burnetii, agent de la fièvre Q

Contact Info

Product

Resources

About