Polyimide (PI) is an ideal flyer material commonly used for exploding foil initiator (EFI) systems. The material properties of PI influence the flight ability of the flyer. Curing temperature during the preparation process of PI is one of the key factors influencing the material properties. In this study, we investigated the effect of the PI film curing temperature on the material properties and the flight ability by characterizing IR transmittance, XPS, and nano-hardness. The results show that the flight ability of the flyer is highly dependent on the curing temperature. Curing at 250 C is beneficial for the flyer to have an optimal flight velocity, which was attributed to the good chemical and mechanical behavior of the material. Increase in curing temperature would weaken the material properties to some extent.High-temperature cure (e.g., 400 C), would break the molecular chain and carbonize the material, causing significant drop in flight velocity of the flyer. The study is expected to contribute to the development of high-performance flyer for EFI applications.