Pyuria and Urine Cultures in Patients with Acute Renal Colic

Dorfman, M.; Chan, S.B.; Hayek, Kevin; Hill, Colin

doi:10.1016/j.jemermed.2015.10.043

Cited by 11 publications

(6 citation statements)

References 9 publications

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“…[18] The degree of pyuria is a strong predictor of positive culture, although pyuria itself is a poor indicator of urinary tract infection in patients with renal stones. [19]…”

Section: Discussionmentioning

confidence: 99%

“…[18] The degree of pyuria is a strong predictor of positive culture, although pyuria itself is a poor indicator of urinary tract infection in patients with renal stones. [19] After 4-6 weeks of stone clearance, a single 24-hour urine sample was collected and examined according to the study protocol. However, the use of single versus double 24-hour urine in biochemistry is currently being debated.…”

Section: Discussionmentioning

confidence: 99%

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Metabolic evaluation of first-time uncomplicated renal stone formers: A prospective study

Ranjan¹,

Mittal²,

Mirza³

et al. 2022

Curr Urol

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Background: Nephrolithiasis is a global health problem. The recurrence rate after the first stone clearance is approximately 50% at 5 years. Metabolic abnormalities are an important factor responsible for stone recurrence. Our prevalidated study aimed to evaluate metabolic abnormalities associated with first-time uncomplicated renal stone formers (FTURSF). Materials and methods: In this prospective, exploratory, time-bound, descriptive study, 30 first-time renal stone formers were evaluated for metabolic abnormalities. High-risk stone formers were excluded from the study. Data were collected in a predefined proforma, transferred to an Excel sheet, and analyzed using the Statistical Package for Social Sciences 20 and Epi Info 7. Fisher exact test, Mann-Whitney U test, paired t test, and Pearson correlation coefficient were used for statistical analyses. Results: The mean age of the participants was 35.57 ± 11.07 years, with a male-to-female ratio of 1.72. The most common abnormality was a 24-hour urine volume of <2.5 L in 73.33% of the participants. One or more metabolic abnormalities were detected in 76.67% of the participants. Other common metabolic abnormalities detected were hypocitraturia (60%), hypercalciuria (16.67%), hyperoxaluria (13.33%), and hyperuricosuria (3.33%). Parathyroid adenoma was detected in one participant (3.33%). Conclusions: Our study documented significant metabolic abnormalities in FTURSF. Therefore, a simplified metabolic evaluation protocol should be adopted while evaluating FTURSF. Detection of an underlying metabolic abnormality would enable the early institution of preventive measures to reduce stone recurrence and related complications.

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“…[18] The degree of pyuria is a strong predictor of positive culture, although pyuria itself is a poor indicator of urinary tract infection in patients with renal stones. [19]…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Metabolic evaluation of first-time uncomplicated renal stone formers: A prospective study

Ranjan¹,

Mittal²,

Mirza³

et al. 2022

Curr Urol

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“…A study by Shih et al reported the correlation of epidemiological and clinical parameters with pain severity. Other studies by Lallas et al, Dorfman et al, and Sasmaz and Kirpat reported a significant correlation of pain severity with hematuria and pyuria [7][8][9][10]. Gourlay et al and Splinter et al reported that there was no significant correlation of pain with stone size, location, and patient outcomes.…”

Section: Introductionmentioning

confidence: 91%

“…Severity of pain: Visual Analogue Scale (VAS) 0 to 10 (0=no pain, 1-3=mild, 4-6=moderate, 7-10=severe) [16] 2. Hematuria: more than or equal to 5 red blood cells per high power field [9] 3. Pyuria: more than or equal to 10 pus cells per high power field [9] 4.…”

Section: Figure 1: Study Flowchartmentioning

confidence: 99%

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Correlation of Severity of Renal Colic With Clinical, Laboratory, and Radiological Parameters: An Emergency Department-Based Prospective Observational Study

Joshi¹,

Kaeley²,

Nagasubramanyam³

et al. 2022

Cureus

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In this study, we investigated the correlation of severity of renal colic with clinical parameters like pain characteristics, haematuria and pyuria, laboratory parameters such as inflammatory markers, and radiological parameters including site and size of stone and hydronephrosis. MethodsThe Visual Analogue Scale (VAS) determined the pain severity. Detailed history and clinicodemographic profiling of the patient was done, laboratory investigations were done, ultrasound and non-contrast computed tomography of kidney-ureter-bladder were done and all the parameters were duly noted and correlated with the pain severity. ResultThe mean age of the 183 patients was 43.96 ± 15.16 years, and 62.8% were male. The patients' mean VAS score at presentation was 8.57 ± 1.08. The mean VAS score was found to be statistically higher in patients having a first episode of renal colic, solitary kidney, pyuria, raised creatinine, severe hydronephrosis, and stones located at the renal pelvis. In addition, higher VAS scores led to more surgical interventions. ConclusionThe correlation of pain severity of renal colic with various parameters can aid in the development of quick diagnostic and therapeutic protocols for patients presenting to the emergency department with renal stone disease. This study shows that pain scores can correlate with various parameters and predict the outcome and complications in these patients.

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The evaluation and management of urolithiasis in the ED: A review of the literature

Gottlieb

Long

Koyfman

2018

The American Journal of Emergency Medicine

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Pyuria and Urine Cultures in Patients with Acute Renal Colic

Cited by 11 publications

References 9 publications

Metabolic evaluation of first-time uncomplicated renal stone formers: A prospective study

Metabolic evaluation of first-time uncomplicated renal stone formers: A prospective study

Correlation of Severity of Renal Colic With Clinical, Laboratory, and Radiological Parameters: An Emergency Department-Based Prospective Observational Study

The evaluation and management of urolithiasis in the ED: A review of the literature

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