1962
DOI: 10.1016/0006-3002(62)90586-3
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Pyruvate oxidation in thyroid tissue

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1963
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Cited by 12 publications
(4 citation statements)
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“…total oxygen consumption (34). This is consornant with the observation that the QO2 of thyroid slices is well-maintained although no substrate is added to the medium (35)(36)(37). The endogenous substrate whose oxidation accounts for most of the oxygen consumed is, however, unknown.…”
Section: Discussionmentioning
confidence: 80%
“…total oxygen consumption (34). This is consornant with the observation that the QO2 of thyroid slices is well-maintained although no substrate is added to the medium (35)(36)(37). The endogenous substrate whose oxidation accounts for most of the oxygen consumed is, however, unknown.…”
Section: Discussionmentioning
confidence: 80%
“…In thyroid tissues, the LDHA and LDHB expression levels were similar in follicular, oncocytic tumors and normal tissues (Figure 1B). The correlation between protein and mRNA levels for LDHA and LDHB was less relevant, but related to previous studies on cell metabolism where a mix between aerobic and anaerobic glycolysis was described in normal and tumor cells [21][22] (Figure S1). …”
Section: Resultsmentioning
confidence: 79%
“…A possible explanation is suggested by the work of Chappell & Greville (1961), who showed that in 2,4-dinitrophenol-treated mitochondria oxidations that were dependent on the conversion of a-oxoglutarate into succinate remained rate-limited by the availability of ADP if oligomycin was also present. In thyroid-slice preparations the respiration is due to citric acidcycle activity, including this oxidation step (Dumont, 1962).…”
Section: Resultsmentioning
confidence: 99%
“…The methods used in the preparation and for the incubation of sheep thyroid slices were as described by Dumont (1964). The slices were incubated in a Warburg apparatus or in a Dubnoff metabolic incubator under an atmosphere of air or oxygen at 37°.…”
Section: Methodsmentioning
confidence: 99%