Abstract:DNA interstrand cross-linking (ICL) is a phenomenon in which two strands of the DNA (most often as part of the same DNA duplex) bind together via a covalent bond. This process prevents the DNA strand dissociation, which is essential for its biological functions, and thus is extremely damaging to cells. To overcome the problem of non-specificity associated with general DNA cross-linking agents, a cross-linkable probe in which the reactive group is placed on the probe that can specifically recognize part of the … Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.