Pyridinium salts of dithiophosphoric acids on the basis of nicotinic acids and their isomers, 3-hydroxypyridine, and 3-pyridinemethanol

3-Hydroxypyridine and 3-(Hydroxymethyl)pyridine in the Synthesis of Salts of Aryldithiophosphonic Acids on the Basis of Monoterpenyl Alcohols

“…The 1 H NMR spectra were obtained on a Bruker Avance-400 (400 MHz) (Bruker BioSpin AG, Fallanden, Switzerland) (400 MHz) or a Bruker Avance-600 (600 MHz) (Bruker BioSpin AG, Fallanden, Switzerland) in in CD3OD-CCl4 (1:1). The 13 { С 1 H} and 13 NMR spectra were registered on a С Bruker Avance-400 (Bruker BioSpin AG, Fallanden, Switzerland) (100.6 MHz) at ambient temperature (s = singlet, d = doublet, t = triplet, q = quartet, sept = septet, m = multiplet). Chemical shifts ( are measured relative to the residual resonance of solvents and given in parts per million (ppm)).…”

“…The use of phosphorus dithioacids in the reactions with pyridine alkaloids is likely to lead to low toxicity organosulfurphosphorus derivatives possessing ionic structures and promising as antimicrobials. Thus, the antimicrobial activity of pyridinium salts of dithiophosphoric acids on the basis of 3hydroxypyridine and 3-pyridinemethanol, as well as the corresponding 3-hydroxypyridinium bisdithiophosphonic acids, was recently established (13,14). In the development of research on synthesis of antimicrobial pyridinium salts of phosphorus dithioacids, we turned to chiral dithiophosphonic acids on the basis of optically active monoterpenyl alcohols as well as racemic and aryl monoterpenyl alcohols.…”