1988
DOI: 10.1002/ardp.19883210515
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Pyridazines XXX VIIII. Pyridazino[4,5–e]‐1,4‐diazepine – A Novel Ring System of Potential Pharmaceutical Interest

Abstract: Since Sternbach's discovery of the benzodiazepines there has been enormous effort to optimize as well as to alter the pharmacological profile of these important drug substances3). In this context, a great number of structure modifications has been concerned with the replacement of the "benzo" moiety by heteroaromatic systems, including various N-hetero-cycles4). Despite the continuing interest in pyrido-1,4-diazepines4-'), the corresponding aza-analoguous diazino-annelated systems so far remained largely unexp… Show more

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Cited by 8 publications
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