Pyrazine Based Type‐I Sensitizing Assemblies for Photoreduction of Cu(II) in ‘One‐Pot Three‐Component’ CuAAC Reaction Under Aerial Conditions

Abstract

Photosensitizing assemblies of pyrazine derivative PDA have been developed which exhibit a high photostability, 'lighted' excited state, balanced redox potential, high transportation potential and activate oxygen via type-I pathway only. These PDA assemblies in combination with Cu(II) ions catalyze the CuAAC reaction via in situ reduction of Cu(II) ions without any reducing or stabilizing agent. The present protocol has wide substrate scope with recyclability of the catalytic system up to six catalytic cycles and is applicable to gram-scale synthesis.

A comparative study of two thienopyrimidine Schiff base probes for sequential monitoring of Ga3+ and Pd2+

“…Schiff bases, known for their high coordination affinity for metal ions, find extensive applications in organic and medicinal chemistry owing to their ease of synthesis [47–52]. However, the issue lies in the poor biocompatibility or insufficient water solubility of ordinary Schiff base molecules, which may impede their utility.…”

Enzyme-/metal-free quinoxaline assemblies: direct light-up detection of cholesterol in human serum

“…We believe that due to the presence of diphenylamino groups, the QxP derivative is intrinsically hydrophobhic and hence displays less conspicuous emission change in the presence of cholesterol-mediated exclusion of polar protic solvents. Furthermore, we also examined the response of quinoxaline derivatives QxCHO 18 and QxTPY 19 towards cholesterol (Fig. 2).…”