Pyostomatitis Vegetans

McCarthy, Francis P.

doi:10.1001/archderm.1949.01530050112010

Cited by 70 publications

(6 citation statements)

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“…McCarthy (1949) proposed the term “pyostomatitis vegetans” after he observed similar lesions isolated in the oral cavity (McCarthy, 1949; Femiano et al 2009). Recently these two entities are considered to be variants of the same disease termed pyodermatitis–pyostomatitis vegetans (PPV; Ficarra et al, 2010).…”

Section: Reactive Cutaneous Manifestations Of Ibdmentioning

confidence: 99%

Skin Manifestations of Inflammatory Bowel Disease

2012

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Inflammatory bowel disease (IBD) is a disease that affects the intestinal tract via an inflammatory process. Patients who suffer from IBD often have diseases that affect multiple other organ systems as well. These are called extraintestinal manifestations and can be just as, if not more debilitating than the intestinal inflammation itself. The skin is one of the most commonly affected organ systems in patients who suffer from IBD. The scientific literature suggests that a disturbance of the equilibrium between host defense and tolerance, and the subsequent over-activity of certain immune pathways are responsible for the cutaneous disorders seen so frequently in IBD patients. The purpose of this review article is to give an overview of the types of skin diseases that are typically seen with IBD and their respective pathogenesis, proposed mechanisms, and treatments. These cutaneous disorders can manifest as metastatic lesions, reactive processes to the intestinal inflammation, complications of IBD itself, or side effects from IBD treatments; these can be associated with IBD via genetic linkage, common autoimmune processes, or other mechanisms that will be discussed in this article. Ultimately, it is important for healthcare providers to understand that skin manifestations should always be checked and evaluated for in patients with IBD. Furthermore, skin disorders can predate gastrointestinal symptoms and thus may serve as important clinical indicators leading physicians to earlier diagnosis of IBD.

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Section: Reactive Cutaneous Manifestations Of Ibdmentioning

confidence: 99%

Skin Manifestations of Inflammatory Bowel Disease

2012

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“…Pyostomatitis vegetans is a rare disorder characterized by erythema and pebbly edema of the oral mucosa and numerous superficial pustules. Although it is more common in ulcerative colitis, it has also been associated with Crohn's disease and overlap disease (that is, inflammatory bowel disease possessing features of both ulcerative colitis and Crohn's disease) (38,84,94). The pustules show a predilection for the facial gingiva, buccal and tonsillar mucosa and palate.…”

Section: Oral Manifestationsmentioning

confidence: 99%

Crohn's disease: orofacial considerations and disease pathogenesis

Kalmar

1994

Periodontology 2000

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“…Cutaneous lesions are typically vesicopustular, exudative and vegetative, and are usually localized on the face, scalp, axilla, genitalia and, less commonly, on the abdomen, trunk and distal parts of the extremities. In 1949, McCarthy reported a case with oral mucosa lesions without associating cutaneous findings and named the condition "pyostomatitis vegetans" (2). Today, these two diseases are considered to be different manifestations of the same entity.…”

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confidence: 99%