Pyomyositis masquerading as suprapubic mass: An unusual presentation of melioidosis

Chang, Chee Yik

doi:10.4038/cmj.v66i2.9475

Cited by 1 publication

(2 citation statements)

References 5 publications

(10 reference statements)

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“…It is important to complete the treatment to prevent relapse of melioidosis. Furthermore, surgical drainage of musculoskeletal abscesses is the mainstay of treatment of melioidosis, in conjunction with antimicrobial therapy [ 17 ]. Treated patients require long-term follow-up due to the organism showing latency of up to 26 years in the body [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

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Emerging Burkholderia Musculoskeletal Infections With Delayed Diagnosis in Non-endemic Regions Affect Patient Morbidity: A Case Series of 10 Patients With a Review of the Literature

Kumar,

Bhambhu,

Gugale

et al. 2024

Cureus

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Introduction: Burkholderia infection commonly presents as bacteraemic pulmonary disease; however, it is notorious for its wide variety of presentations in chronic cases, including musculoskeletal manifestations. It is common in patients living in endemic areas with comorbidities such as diabetes and who have chronic alcoholism. It was previously under-reported due to a low index of suspicion. Now, there is an increasing trend of diagnosis of these infections in non-endemic areas because of various factors, such as MALDI-TOF, molecular tests, and PCR. Materials and methods: This is a single tertiary centre study of 10 patients, diagnosed with Burkholderia infection and treated at our institution between 2021 and 2023 and followed up for a minimum of six months. Information was collected from outpatient and inpatient records. Results: In this study, the mean age of the patients was 45 years, with eight males and two females. Out of 10, seven patients had comorbidities. However, only one patient has a history of travelling to an endemic area. All our patients were treated operatively, and the course of intervention and the planning of the surgical procedure were decided according to clinico-radiological findings. Six out of 10 patients suffering from Burkholderia species infections have a history of prolonged ICU stay, four of them tested positive for Burkholderia pseudomallei and the remaining two tested positive for Burkholderia cepacia, with a mean average time of 24.6 days. Diabetes was the most common comorbidity in 70% of the patients. The knee was the most commonly affected joint, showing involvement in 60% of patients. We have done surgical intervention in all patients. In our study, we have given IV antibiotics for a minimum of six weeks to all patients, followed by oral antibiotic therapy for three to six months on the basis of regular follow-up of clinico-haematologic parameters. Conclusion: Infections caused by Burkholderia species should be considered a potential causative agent of musculoskeletal infections in non-endemic areas without prior history of travelling to endemic areas. It may present with a chronic, mild course; a high index of suspicion is required, and it is important that due suspicion translates to prompt diagnosis and appropriate treatment to mitigate the course of the disease and associated morbidities in patients.

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Section: Discussionmentioning

confidence: 99%

“…therapy [17]. Treated patients require long-term follow-up due to the organism showing latency of up to 26 years in the body [12].…”

Section: Discussionmentioning

confidence: 99%

Emerging Burkholderia Musculoskeletal Infections With Delayed Diagnosis in Non-endemic Regions Affect Patient Morbidity: A Case Series of 10 Patients With a Review of the Literature

Kumar,

Bhambhu,

Gugale

et al. 2024

Cureus

View full text Add to dashboard Cite

show abstract

Pyomyositis masquerading as suprapubic mass: An unusual presentation of melioidosis

Cited by 1 publication

References 5 publications

Emerging Burkholderia Musculoskeletal Infections With Delayed Diagnosis in Non-endemic Regions Affect Patient Morbidity: A Case Series of 10 Patients With a Review of the Literature

Emerging Burkholderia Musculoskeletal Infections With Delayed Diagnosis in Non-endemic Regions Affect Patient Morbidity: A Case Series of 10 Patients With a Review of the Literature

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