Pyometra in the Queen: Evaluation of Different Methods of Treatment

Abstract

Pyometra is a common disease of female cats (queens) characterized by endometrial hyperplasia with cystic dilation of endometrial glands and accumulation of the neutrophil-rich exudate in the uterine lumen. In this study, 20 queens with the age range of 10 to 108 months (average 26 months) and diagnosed with pyometra (open and closed) between January 2019 and January 2021 were divided into four groups A, B, C and D, with five queens in each group. A first dose of Alizin® was given at 10mg/kg (S/C) to animals of groups A, B and C. In group A, the second dose of Alizin® was given 24hrs later while monitoring for vaginal discharge. In group B, upon notice of vaginal discharge at 24hrs, a dose of PGF 2α was given at 1.0mcg/kg BW (S/C) which eventually stopped the discharge. In group C, upon notice of vaginal discharge at 24hrs, a dose of Cytotec® was given intravaginally as 100mcg/cat. Group D was subjected to ovariohysterectomy and no complication was noted for 7 days post operation; on the 14th day, sutures were removed, and the surgical site healed completely. Vaginal discharge was noticed post Alizin® administration in groups A, B and C. Responses in three groups were observed 24 and 48hrs post treatment. In groups B and C, there was evidence of higher evacuated uterine pus compared to group A. Group C was better with no evidence of rapid respiration compared to groups B and A. There was evidence of general health response with the maximum resumption of feeding in groups B and C. In conclusion, the current study elucidated a different dimension for treating pyometra with an advantage of recovery and complete healing coupled with the response of maximum feeding for groups treated with Alizin in combination with PGF 2 or Misoprostol.

The Efficiency of Melatonin Hormone Implantation in Suppressing the Estrus Cycle in Domesticated Queens (Felis catus)

“…C ats are animals with highly efficient reproduction (Hassan and Saleh, 2022). The challenge of cat overpopulation is a global issue with severe consequences, including the spread of disease, and the euthanasia of millions of cats yearly (Al-Zubaidi et al, 2024). The main objective of contraceptives, fertility control in cats is to prevent reproduction by preventing the estrus cycle in females, including vocalization, rolling on the ground and a very short interestrus period, and male sexual behaviors, especially urine spraying ( Johnson, 2022), owned cats and ultimately helped the management of catteries (Root Kustritz, 2018).…”