Pyogenic ventriculitis following urosepsis caused by<i>Escherichia coli</i>

Kobayashi, Hiroyuki; Suzuki, Tomoharu; Tokuda, Yasuharu

doi:10.1136/bcr-2013-201148

Cited by 5 publications

(4 citation statements)

References 1 publication

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“…In both these cases the initial diagnosis was urinary infection, but an altered mental status led to a subsequent study, with pyogenic ventriculitis being diagnosed. As in our case, E. coli was the bacterial agent implied as it grew on blood, urine and cerebrospinal fluid cultures [4,5] . We could only isolate E. coli in blood and urine cultures, probably because the patient was already on his fifth day of antibiotic, so we think it is reasonable to assume that the agent responsible for the pyogenic ventriculitis was E. coli.…”

Section: Discussionsupporting

confidence: 59%

“…We used an antibiotic regimen of ceftriaxone 2 g, 12/12h (the so called 'meningeal dose') for 6 weeks, even though there were no clinical guidelines to support it. In the two cases similar to ours, this was also the antibiotic regimen chosen, also with a good outcome [4,5]. The few cases published and the multitude of microorganisms implicated make it difficult to generate a universal recommendation, but the consensus seems to be to use long antibiotic regimens [1,6] .…”

Section: Discussionmentioning

confidence: 57%

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Pyogenic Ventriculitis Associated with Urosepsis: A Rare Case Report

Lopes

Basílio²,

Amaro

2020

European Journal of Case Reports in Internal Medicine

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Pyogenic ventriculitis is an infection of the cerebral ventricles usually associated with neurosurgery or head trauma. There are less than 10 reported cases of community-acquired pyogenic ventriculitis in adults. We present the case of a 71-year-old man with a medical history of type 2 diabetes mellitus, hospitalized due to urosepsis caused by E. coli. Because he had a fluctuant level of consciousness, he underwent magnetic resonance imaging that diagnosed pyogenic ventriculitis. He was treated with ceftriaxone 2 g 12/12h for a total of 6 weeks and recovered without neurological deficits. Pyogenic ventriculitis is a clinical challenge due to its rarity, atypical presentation and variety of aetiological microorganisms.

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Section: Discussionsupporting

confidence: 59%

Section: Discussionmentioning

confidence: 57%

Pyogenic Ventriculitis Associated with Urosepsis: A Rare Case Report

Lopes

Basílio²,

Amaro

2020

European Journal of Case Reports in Internal Medicine

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“…CT has limitations in differentiating intraventricular pus and hemorrhage, and are less sensitive in early phase of ventricular infection2). One report shows initial CT did not present an intraventricular lesion until clinical deterioration after two days, delaying diagnosis and treatment of the patient 5) .…”

Section: Discussionmentioning

confidence: 99%

Ventriculitis Associated with Invasive <italic>Klebsiella Pneumoniae</italic> Syndrome: A Case Report

Kim

Hur

Kim

et al. 2023

Nerve

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Invasive Klebsiella pneumoniae syndrome is defined as community-acquired liver abscess and metastatic infections in the lung, soft tissue, and central nervous system (CNS) caused by hypervirulent Klebsiella pneumoniae. Metastatic CNS infection in invasive Klebsiella pneumoniae syndrome shows rapid clinical deterioration and a high mortality rate. We present a case of ventriculitis caused by invasive Klebsiella pneumoniae syndrome successfully treated with a timely diagnosis, immediate surgical intervention, and administration of antibiotics.

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“…Lacking rapid diagnosis and treatment, pyogenic ventriculitis may result in hydrocephalus and even death. In adults, ventriculitis is generally recognized as complication of brain abscess, meningitis extension, or neurosurgery (7). In contrast, primary pyogenic ventriculitis is even rarer.…”

Section: Introductionmentioning

confidence: 99%

The first report of human primary pyogenic ventriculitis caused by Streptococcus suis: a case report

Pang¹,

Ma²,

Zhuo³

et al. 2021

Ann Palliat Med

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Streptococcus suis (S. suis), a gram-positive facultative anaerobe, has emerged as a zoonotic pathogen of suppurative infections in various human organs. Never reported is human primary ventriculitis caused by S. suis. A 70-year-old Chinese woman with a history of eating undercooked pork tongue was admitted to our hospital due to vomiting, headache and high fever. Brain magnetic resonance imaging (MRI) revealed intraventricular empyema and hydrocephalus, while cerebrospinal fluid (CSF) analysis showed purulent changes. S. suis was cultured in the CSF and blood samples of the patient, and confirmed as serotype 2 by real-time polymerase chain reaction (PCR). Therefore, the diagnosis of primary ventriculitis caused by S. suis was established. She was treated with intravenous (IV) meropenem for six weeks. To solve hydrocephalus, external ventricular drain (EVD) was performed, followed by ventriculoperitoneal shunt.Finally, the patient achieved a good outcome after a 6-month follow-up. S. suis is a rare pathogen in northern China but can cause severe infection and complications. S. suis infection should be considered when a patient with bacterial infection has a history of eating undercooked pork. MRI can help detect ventriculitis.It is worth noting that rapid and prolongated administration of IV antibiotics and timely neurosurgical intervention can achieve desirable outcomes.

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Pyogenic ventriculitis following urosepsis caused byEscherichia coli

Cited by 5 publications

References 1 publication

Pyogenic Ventriculitis Associated with Urosepsis: A Rare Case Report

Pyogenic Ventriculitis Associated with Urosepsis: A Rare Case Report

Ventriculitis Associated with Invasive <italic>Klebsiella Pneumoniae</italic> Syndrome: A Case Report

The first report of human primary pyogenic ventriculitis caused by Streptococcus suis: a case report

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