Pyogenic Granuloma of the Cornea in an Infant With Unilateral Microphthalmia

Karatza, Ekaterini C.; Calhoun, Joseph H.; Eagle, Ralph C.

doi:10.1001/archopht.121.8.1197

Cited by 6 publications

(23 citation statements)

References 15 publications

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“…The size of the mass in our patient was within the range of the reported cases which is 3×3mm to 8x9mm. Most of the patients with pyogenic granuloma of the cornea had a rapid course with presentation within one month of the onset of the growth (6–8) which was also the case in our patient.…”

Section: Discussionsupporting

confidence: 82%

“…The commonest clinical presentation of the corneal pyogenic granuloma is a rapidly growing lump which, on slit lamp examination, appears as well circumscribed, smooth surfaced, pink, sessile, and highly vascularized mass (2, 6, 7). Our patient had a similar clinical presentation.…”

Section: Discussionmentioning

confidence: 99%

“…Cornea pyogenic granuloma commonly grows at the sites of pre-existing corneal trauma or corneal ulcer due to infectious keratitis which are the two commonly identified risk factors (1, 2, 6, 7, 9). Our patient also had infectious keratitis as a risk factor.…”

Section: Discussionmentioning

confidence: 99%

“…The typical histopathological finding of pyogenic granuloma is an excessive proliferation of granulation tissue with mononuclear cell infiltration (2, 6, 7). …”

Section: Discussionmentioning

confidence: 99%

“…There were cases misdiagnosed as conjunctival squamous cell carcinoma and ended with enucleation (5, 11). Other differential diagnoses include anterior segment choristoma, a vascular hamartoma or a viral papilloma (6). The age of onset, history of prior trauma or infection, rapid growth and the clinical appearance will often point to the correct diagnosis.…”

Section: Discussionmentioning

confidence: 99%

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Case Report: Corneal Pyogenic Granuloma: Rare Complication of Infectious Keratitis

Abateneh¹,

Bekele²

2014

Ethiop J Health Sci

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BackgroundPyogenic granuloma is an excessive proliferation of granulation tissue that usually develops after minor trauma or surgery. Ocular involvement usually happens on the external surface and cornea is rarely involved. The objective of our report is to describe the clinicopathological feature of this rare disease and give insight on clinical features that help in the diagnosis.Case ReportThis report presents a case of a four year old child who had fleshy growth of one week duration on the right eye after seven weeks of pain and redness. Slit lamp examination showed vascularized central corneal mass with surrounding stromal infiltrates. The mass was excised, and histopathological examination confirmed pyogenic granuloma of the cornea.ConclusionCorneal pyogenic granuloma could be a rare complication of infectious keratitis. Therefore, it should be considered as a differential diagnosis in corneal mass especially after an infection or trauma.

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Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…The typical histopathological finding of pyogenic granuloma is an excessive proliferation of granulation tissue with mononuclear cell infiltration (2, 6, 7). …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Case Report: Corneal Pyogenic Granuloma: Rare Complication of Infectious Keratitis

Abateneh¹,

Bekele²

2014

Ethiop J Health Sci

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Vulvar Lobular Capillary Hemangioma (Pyogenic Granuloma)

Chong¹,

Yeh²,

Hwang³

2005

Taiwanese Journal of Obstetrics and Gynecology

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Pyogenic granuloma of the cornea in a pony: Uncommon complication of corneal wound healing

Régnier

Landrevie

Robin

et al. 2022

Veterinary Ophthalmology

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A 6‐year‐old miniature Shetland pony mare was referred for evaluation of a left corneal mass, which developed from the healing tissue of a corneal traumatic ulceration that had occurred 4 weeks previously. On gross examination, a spherical, smooth‐surfaced, and pink‐colored lesion of about 1 cm in diameter was protruding from the left palpebral fissure. Ophthalmic examination revealed that it was attached to the scar tissue of the cornea, and that one corpora nigra was adherent to the posterior face of corneal wounded area, without sign of uveitis. The remainder of the ophthalmic examination was unremarkable. The mass was excised, and cryotherapy was used as an adjunctive therapy. Histopathology of the resected mass was consistent with a pyogenic granuloma on the basis of radially oriented proliferating capillaries, embedded in immature granulation tissue containing an infiltrate of neutrophils, plasma cells and eosinophils. There were no histological features of malignancy. 2 months after surgery, the ventral part of the fibrotic corneal scar was slightly raised by a pink tissue, suggesting possible recurrence of the initial lesion. A second cryotherapy was performed over the leukoma area. No recurrence has been noted for a follow‐up period of more than 25 months. Pyogenic granuloma is a benign proliferative fibrovascular response that typically develops after trauma or surgery. Corneal involvement is rare in humans, and to the authors' knowledge has never been documented in veterinary ophthalmology.

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Pyogenic Granuloma of the Cornea in an Infant With Unilateral Microphthalmia

Cited by 6 publications

References 15 publications

Case Report: Corneal Pyogenic Granuloma: Rare Complication of Infectious Keratitis

Case Report: Corneal Pyogenic Granuloma: Rare Complication of Infectious Keratitis

Vulvar Lobular Capillary Hemangioma (Pyogenic Granuloma)

Pyogenic granuloma of the cornea in a pony: Uncommon complication of corneal wound healing

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