Pyogenic bacterial lower respiratory tract infection in human immunodeficiency virus-infected patients

Mayaud, C; Parrot, Antoine; Cadranel, Jacquès

doi:10.1183/09031936.02.00400602

Cited by 41 publications

(32 citation statements)

References 128 publications

(192 reference statements)

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“…The lower respiratory tract infections are the most frequent respiratory diseases among HIV infected patients and are frequently the first clinical manifestations of the HIV infections [6]. In Nepal, concerns on LRTIs are increasing among the HIV infected cases because they are being revealed as the important opportunistic infections among these cohorts.…”

Section: Introductionmentioning

confidence: 99%

“…LRTIs are common not only among the HIV sero-positive cases but also the commonest domiciliary and nosocomial infections among the general population [9]. The risk of development of invasive pneumococcal diseases is higher among the HIV positive cases than the HIV sero-negative population [6]. Diverse types of organisms including Gram positive and Gram negative bacteria, Mycobacterium and fungal pathogens are responsible for LRTIs.…”

Section: Introductionmentioning

confidence: 99%

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Lower respiratory tract infections among HIV positive and control group in Nepal

et al. 2015

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Lower respiratory tract infections among HIV positive and control group in Nepal

et al. 2015

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“…According to these authors the main pyogenic bacteria responsible for pneumonia in these patients were Streptococcus pneumoniae and, to a lesser degree, Haemophilus influenzae, in adults as well as children in both developed and developing countries. In the HAART era, some studies have observed a decrease in the number of cases of bacterial pneumonia (Mayaud, Parrot, Cadranel, 2002), while other authors have shown that this decrease was mainly observed for nosocomial pneumonia and remained nonsignificant for community-acquired pneumonia.…”

Section: Antiretroviral Drugs and Viral Agentsmentioning

confidence: 98%

“…(Table III) Respiratory tract bacterial (pyogenic and nonpyogenic) infections in human immunodeficiency virus-infected patients are the most frequent respiratory disease but other sites may also be compromised. In the pre-HAART era the incidence of most common opportunistic infections such as bronchitis and pneumonia could be partially prevented by the use of prophylaxis (Mayaud, Parrot, Cadranel, 2002). According to these authors the main pyogenic bacteria responsible for pneumonia in these patients were Streptococcus pneumoniae and, to a lesser degree, Haemophilus influenzae, in adults as well as children in both developed and developing countries.…”

Section: Antiretroviral Drugs and Viral Agentsmentioning

confidence: 99%

Activity of antiretroviral drugs in human infections by opportunistic agents

Demarchi

Cardozo

Aristides

et al. 2012

Braz. J. Pharm. Sci.

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Highly active antiretroviral therapy (HAART) is used in patients infected with HIV. This treatment has been shown to significantly decrease opportunist infections such as those caused by viruses, fungi and particularly, protozoa. The use of HAART in HIV-positive persons is associated with immune reconstitution as well as decreased prevalence of oral candidiasis and candidal carriage. Antiretroviral therapy benefits patients who are co-infected by the human immunodeficiency virus (HIV), human herpes virus 8 (HHV-8), Epstein-Barr virus, hepatitis B virus (HBV), parvovirus B19 and cytomegalovirus (CMV). HAART has also led to a significant reduction in the incidence, and the modification of characteristics, of bacteremia by etiological agents such as Staphylococcus aureus, coagulase negative staphylococcus, non-typhoid species of Salmonella, Streptococcus pneumoniae, Pseudomonas aeruginosa, and Mycobacterium tuberculosis. HAART can modify the natural history of cryptosporidiosis and microsporidiosis, and restore mucosal immunity, leading to the eradication of Cryptosporidium parvum. A similar restoration of immune response occurs in infections by Toxoplasma gondii. The decline in the incidence of visceral leishmaniasis/HIV co-infection can be observed after the introduction of protease inhibitor therapy. Current findings are highly relevant for clinical medicine and may serve to reduce the number of prescribed drugs thereby improving the quality of life of patients with opportunistic diseases.
A terapia HAART (terapia antirretroviral altamente ativa) é usada em pacientes infectados pelo vírus da imunodeficiência humana (HIV) e demonstrou diminuição significativa de infecções oportunistas, tais como as causadas por vírus, fungos, protozoários e bactérias. O uso da HAART está associado com a reconstituição imunológica e diminuição na prevalência de candidíase oral. A terapia antirretroviral beneficia pacientes co-infectados pelo HIV, vírus herpes humano 8 (HHV-8), vírus Epstein-Barr (EBV), vírus da hepatite B (HBV), parvovírus B19 e citomegalovírus (CMV). A HAART também apresentou redução significativa da incidência e modificou as características da bacteremia por agentes etiológicos, tais como Staphylococcus aureus, espécies não-tifóides de Salmonella, Streptococcus pneumoniae, Pseudomonas aeruginosa, Mycobacterium tuberculosis. A HAART é capaz de modificar significativamente a história natural da criptosporidiose e microsporidiose. HAART pode efetivamente restaurar a imunidade da mucosa, levando à erradicação de Cryptosporidium parvum. Semelhante restauração da resposta imune ocorre em infecções por Toxoplasma gondii. O declínio na incidência de co-infecção leishmaniose visceral/HIV pode ser observada após a introdução da terapia com inibidores da protease. Os resultados atuais são altamente relevantes para a medicina clínica e podem proporcionar diminuição no número de prescrições medicamentosas e, consequentemente, melhor qualidade de vida para pacientes com doenças oportunistas

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“…La tuberculose (TB) reste la première IO inaugurale du SIDA dans le monde ; elle est responsable de près d'un quart des décès [3]. La pneumopathie bacté-rienne est devenue l'atteinte respiratoire la plus fré-quente chez les personnes vivant avec le VIH (PVVIH), quel que soit le degré d'immunodépres-sion [4].…”

Section: Introductionunclassified

Impact of HIV infection on the development of respiratory disease in the Pneumo-Phtisiology Department of CHU Brazzaville from 2006 to 2013

2015

JFVP

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Pyogenic bacterial lower respiratory tract infection in human immunodeficiency virus-infected patients

Cited by 41 publications

References 128 publications

Lower respiratory tract infections among HIV positive and control group in Nepal

Lower respiratory tract infections among HIV positive and control group in Nepal

Activity of antiretroviral drugs in human infections by opportunistic agents

Impact of HIV infection on the development of respiratory disease in the Pneumo-Phtisiology Department of CHU Brazzaville from 2006 to 2013

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