Pyodermatitis-pyostomatitis vegetansReport of a case and review of the literature

Pyodermatitis?Pyostomatitis Vegetans: Two Cases and a Review of the Literature

“…Usually, oral lesions precede or appear simultaneously with cutaneous lesions. Acneiform 28 and psoriasiform 18 changes have also been reported in some patients.…”

“…Pain may occur with erosions (Table II). 18,[20][21][22][23][24][25][26][27][28][29][30][31] Cutaneous involvement is frequent and is seen in 58% of cases. It includes crusting and vegetating erythematous papulopustules coalescing to form large plaques.…”

“…The eruption is asymmetrical and affects mainly the scalp (64%), the vulva (55%), and the groin (20%). Less frequently, other body surfaces may be affected, namely the back, 27,30 the chest, 27 the breasts, 31 the limbs, 30,18 and the perianal area. Usually, oral lesions precede or appear simultaneously with cutaneous lesions.…”

“…Immunofluorescence allows easy differentiation of pemphigus vegetans from PD-PSV; direct and indirect immunofluorescence examinations are usually negative in the latter. 14,18,27,[29][30][31] However, a weakly positive direct immunofluorescence does not rule out PD-PSV. Some reported cases of PD-PSV were probably genuine cases of pemphigus vegetans or pemphigoid.…”

“…Since the initial description, most reports in the literature support the fact that pyostomatitis vegetans and pyodermatitis vegetans pertain to the same disease process. 18 PD-PSV is associated with inflammatory bowel disease. In 1949, Brunsting 19 reported five patients with pyodermatitis vegetans and ulcerative colitis.…”