Pyoderma gangrenosum in burns: A report of 3 cases and review of the literature

Pyoderma Gangrenosum Complicating a Skin Graft for Burns

“…C.C. West et al, [7] in 2010 reported three cases of PG in burns. To our knowledge only two case reports of PG following the skin grafting operation for a non-healing traumatic ulcer were described in literature, first by Klevanski.…”

Severe pyoderma gangrenosum in association with a flame burn

“…[ 10 ] Among various types of injuries, breast surgery is the most known cause of PG,[ 10 , 19 ] whereas the onset of PG due to burn injuries has rarely been reported. [ 12 , 13 ] Interestingly, the serum IL-8 levels are similar in burn patients and subjects who undergo breast operation, rising one day after injury in both conditions and staying at a high level for some time. [ 20 , 21 ] These findings indicate that these pathological states have a similar background.…”

“…[ 10 , 11 ] However, burn wounds have not been recognized to be an etiology of PG, and an association with PG in patients with burn wounds has been infrequently reported. [ 12 , 13 ] In this report, we describe a rare case of widespread PG occurring on grafted skin following burn treatment.…”

Inpatient Management of Pyoderma Gangrenosum

“…19,20 Long et al 38 have propose various strategies to minimize perioperative pathergy, including using subcuticular sutures rather than sutures going through the skin. Adjuvant surgical interventions, including aggressive ulcer excision, recipient-site preparation, grafting of autologous cultured keratinocytes, skin as well as muscle f lap coverage, have only been shown to be effective after PG was rendered quiescent with systemic immunosuppressive therapy.…”