Pyoderma gangrenosum et syndrome de Sweet pédiatriques : étude rétrospective multicentrique

Bucchia, M.; Barbarot, S.; Meinzer, Ulrich; Wallach, D.; Piram, Maryam; Bégon, É.; Mahé, E.; Balguérie, X.; Mallet, S.; Phan, A; Jean, Sara Elisabeth; Reumaux, Héloïse; Hatchuel, Yves; Merlin, E.; Decramer, Stéphane; Lacour, J; Bourrat, E.

doi:10.1016/j.annder.2017.09.080

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“…At present, there is little epidemiological data on PG, and the literature shows that its incidence, age at onset, and sex preference differ, likely due to diagnostic difficulty and the lack of a gold diagnostic standard recognized by consensus. However, an analysis of the literature revealed that the incidence of PG is relatively low, the age distribution is wide [including infants, which account for approximately 4% of cases of PG and the elderly (11, 12)], and it has also been reported in pregnant women (13,14). Statistics published by British scholars showed that the incidence was 0.63/100,000 individuals, the sex difference was not significant (male vs. female = 41% vs. 59%), and the median age at onset was 59 years (15).…”

Section: Clinical Features 21 Epidemiologymentioning

confidence: 99%

Practical aspects of the diagnosis and management of pyoderma gangrenosum

Chen

2023

Front. Med.

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Pyoderma gangrenosum (PG) is a rare autoinflammatory ulcerative neutrophilic skin disease. Its clinical presentation is a rapidly progressing painful skin ulcer with ill-defined borders and surrounding erythema. The pathogenesis of PG is complex and not fully understood. Clinically, patients with PG often have various systemic diseases, the most common being inflammatory bowel disease (IBD) and arthritis. Due to the lack of specific biological markers, diagnosing PG remains difficult, which easily resulting in misdiagnosis. Some validated diagnostic criteria have been applied in clinical practice that facilitate its diagnosis. The treatment of PG currently consists mainly of immunosuppressive and immunomodulatory agents, especially biological agents, which have bright prospects for PG therapy. After the systemic inflammatory response is controlled, the problem of wounds becomes the main contradiction in PG treatment. Surgery is not controversial for PG, increasing evidence shows that with adequate systemic treatment, the benefits of reconstructive surgery for patients are increasing.

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Section: Clinical Features 21 Epidemiologymentioning

confidence: 99%

Practical aspects of the diagnosis and management of pyoderma gangrenosum

Chen

2023

Front. Med.

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Pyoderma gangrenosum et syndrome de Sweet pédiatriques : étude rétrospective multicentrique

Cited by 1 publication

References 0 publications

Practical aspects of the diagnosis and management of pyoderma gangrenosum

Practical aspects of the diagnosis and management of pyoderma gangrenosum

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