Pyoderma gangrenosum: an Indian perspective

Abstract

PG is a rare disease in India, but paediatric PG cases were relatively common. Ulcerative PG was the commonest type, and over half of the patients had associated systemic diseases. There were a significant number of patients with associated systemic disease who had a positive pathergy test.

Pyoderma gangrenosum: An update

“…[1] PG was first described by Brocq in 1916 as “phagedenisme geometrique” and later named by Brunsting et al . [2] The latter author considered PG to be the dissemination of a distant focus of infection (i.e., the bowel in ulcerative colitis or lungs in empyema). [3] Presently PG is considered a reactive inflammatory dermatosis and part of the spectrum of neutrophilic dermatosis.…”

Genital pyoderma gangrenosum

“…Involvement of the perineum is considered pathognomonic of patients with human immunodeficiency virus (HIV). [3] HIV was ruled out in our patient.…”

Pyoderma Gangrenosum—A New Manifestation of Wilson Disease?

“…1 The peak incidence occurs between the ages of 20-50 years with a possible slight female preponderance, and approximately 4% of patients are children. 2 Immunological factors and neutrophil dysfunction can be considered to be involved in etiopathogenesis of pyoderma gangrenosum.…”

“…2 Immunological factors and neutrophil dysfunction can be considered to be involved in etiopathogenesis of pyoderma gangrenosum. 1 The predisposed patient experiences an inciting event such as minor trauma, and instead of normal response that recognises and removes the damaged tissue, the patient's abnormal response results in the typical lesions of the disease. Ulcerative (classic form) is the most common type of pyoderma gangrenosum and the salient feature is a necrotic and mucopurulent tender ulcer with an oedematous, violaceous, serpignously expanding, undermined border as was seen in our patient.…”