Pyoderma caused byPseudomonas aeruginosainfection in dogs: 20 cases

Abstract

In this report we describe the historical, clinical, histopathological and microbiological features, as well as treatments and clinical outcome, of pyoderma where Pseudomonas aeruginosa alone was isolated on bacterial culture from lesional skin. Twenty dogs were included in this retrospective study. Seven dogs without prior history of systemic or skin disease presented with acute deep pseudomonal pyoderma characterized by a sudden onset of dorsal truncal pain. Skin lesions in these dogs consisted of erythematous papules, haemorrhagic bullae, ulcers and haemorrhagic crusts confined to the dorsum. An excellent clinical response was achieved with 3-4 weeks of treatment with oral fluoroquinolones. Thirteen dogs with a more gradual onset of skin lesions associated with pseudomonal pyoderma had a history of prior skin, ear or systemic disease and had previously been treated with antibiotics and/or immunomodulatory drugs. Skin lesions in these dogs were variable and similar to those described for superficial and deep staphylococcal pyoderma. In this group, one dog was euthanized prior to commencement of treatment, two dogs were lost to follow up, and 9 had resolution of lesions following treatment with topical silver sulfadiazine (one dog), fluoroquinolones (six dogs) or cephalexin (two dogs) administered orally for 3 to 12 weeks. Rod-shaped bacteria were not always detected on cytology. Histopathology of dogs with deep pseudomonal pyoderma was characterized by severe perforating suppurative folliculitis and furunculosis.

Antimicrobial effects of cinnamon essential oil and cinnamaldehyde combined with EDTA against canine otitis externa pathogens

“…aeruginosa isolates, common animal pathogens associated with skin and urological infections, were chosen for time‐dependant killing assays (Hillier et al . ; Rutland et al . ; Ducrot et al .…”

Activity of superoxide dysmutase, catalase and glutathione peroxidase in rats exposed to chlorpyrifos and erofloxacin

“…These are synthetic antibacterial chemotherapeutics, with wide spectrum of action used in the treatment of illnesses caused by microorganisms, especially of alimentary, respiratory and urogenital systems diseases, as well as secondary infections in viral diseases (Martínez et al 2006, Gotfried andGrossman 2010) and in veterinary dermatology (Ihrke et al 1999, Hillier et al 2006. Among that group of compounds special attention should be paid to enrofloxacin, which belongs to the second generation of quinolones and has strong antiseptic effect and wide spectrum of action.…”

Successful treatment of a multidrug resistant Pseudomonas aeruginosa infection following a digit amputation in a Belgian Blue calf

“…Although it cannot be proven, the extended antibiotic therapy given to this animal before referral and diagnosis may have played a role in the development of a multidrug resistant P aeruginosa infection. The wound in this case was treated with silver sulfadiazine upon cessation of bandaging as successful treatment with silver sulfadiazine of deep-seated wound infections caused by P aeruginosa has been reported in dogs (Hillier and others 2012). …”