Pyelorenal Backflow during Retrograde Pyelography in Normal and Ischemic
Porcine Kidneys

Thomsen, Henrik S.; Larsen, Svend; Talner, Lee B.

doi:10.1159/000473538

Cited by 29 publications

(10 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As it is known from animal and human studies, with an increase of intrarenal pressure to 20-30 mmHg, pyelo-tubular backflow develops and blood circulation of the kidney decreases (13,14). When intrarenal pressure increases to 30-50 mmHg, the pyelovenous backflow becomes more evident and an increase in both pyelosinus and pyelolymphatic pressures results in forniceal rupture (14,15). It has been reported that a pelvic pressure of ≥30 mmHg during rigid nephrolithotomy was associated with higher pain score and longer hospital stay (16).…”

Section: Discussionmentioning

confidence: 99%

Simultaneous Measurement of Pressure in the Calyces During RIRS in a Human Cadaver Model

Aykaç¹,

Baran²,

Öner³

et al. 2019

jus

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Simultaneous Measurement of Pressure in the Calyces During RIRS in a Human Cadaver Model

Aykaç¹,

Baran²,

Öner³

et al. 2019

jus

View full text Add to dashboard Cite

show abstract

“…The presence of chronic hydronephrosis contributes to tears in the caliceal fornix, which usually occur in an ischemic kidney [5]. Contrast material injected at high pressure may flow into the tubules or may rupture a fornix and flow into the venous system.…”

Section: Discussionmentioning

confidence: 99%

Visualization of the renal vein during pyelography after nephrostomy: a case report

et al. 2010

View full text Add to dashboard Cite

IntroductionWe present a case of pyelovenous backflow after nephrostomy. To the best of our knowledge, this is the first documented case of renal vein visualization after a nephrostomic placement.Case presentationA 55-year-old Caucasian man presented with symptoms of pyelonephritis with an obstructing ureteral stone. A nephrostomy was performed. During an injection of contrast agent in his left caliceal system, his left renal vein was visualized. A repeat pyelography with an injection contrast material at low pressure failed to show the same finding. This radiological finding is due to the occurrence of "pyelovenous backflow".ConclusionThis phenomenon is usually described in the setting of renal vein thrombosis, renal vein hypertension due to the "nutcracker phenomenon", or a reduced renal blood flow. Examination by microscopy shows the presence of tears in the fornix of the pelvic cavity that extend into the kidney parenchyma. Five types of renal backflow are described in the literature: pyelovenous, pyelolymphatic, pyelotubular, pyelointerstitia and pyelosinus. Injection of contrast material at high pressure may cause a fornix to flow into the tubules, or cause its rupture and flow into the venous system.

show abstract

“…Infected urine may also enter the renal interstitium by rupture of the collecting tubes or forniceal rupture. Thomsen and Larsen [114] showed that these tubular ruptures occur at a sustained intrarenal pressure of 30-35 mmHg in the pig, and Jdrgensen et a1 [95] showed in the same animal that kidneys exposed to high pressure reflux because of severe infravesical obstruction show initial lesions in the kidney along the collecting ducts in the cortex (Fig. 15).…”

Section: Factors Influencing Scar Formationmentioning

confidence: 95%

Pathogenetic factors in vesicoureteral reflux

Jørgensen

1986

Neurourology and Urodynamics

View full text Add to dashboard Cite

The pathogenesis of vesicoureteral reflux and reflux nephropathy is multifactorial, but certain known interconnections between different factors have been established. There exists an age-dependent anatomy and function of the ureterovesical junction, and this is of absolute importance for the presence of vesicoureteral reflux. Also, bladder urethral dysfunction with formation of high bladder pressures, urinary tract infections, and ureteric peristaltic properties seem to be of major importance for the development and maintenance of reflux. Vesicoureteral reflux combined with normal bladder-urethral function induces no change in the dynamic function of the upper urinary tract. In cases of bladder-urethral dysfunction that lead to high-pressure reflux, dilatation of the upper urinary tract is produced with irreversible damage of the peristaltic rhythm, frequency, and propagation. Such changes are aggravated by simultaneous infection. Reflux nephropathy most often occurs in cases of pyelorenal backflow with infected urine but can be aggravated by bladder-urethral dysfunction producing high pelvic pressures. Bacteria ascend from the bladder to the kidney, and maximal bladder pressures and the peristaltic conditions in the ureter have an impact on this. The maximal bladder pressure and the compiled pressure load transmitted without hindrance from the bladder to the kidney are presumably mandatory for the formation of nephropathy in cases of sterile reflux.This survey is based on earlier work performed in this laboratory [see 32, 50, 76-78, 94, 95, loo].

show abstract

Pyelorenal Backflow during Retrograde Pyelography in Normal and Ischemic Porcine Kidneys

Cited by 29 publications

References 10 publications

Simultaneous Measurement of Pressure in the Calyces During RIRS in a Human Cadaver Model

Simultaneous Measurement of Pressure in the Calyces During RIRS in a Human Cadaver Model

Visualization of the renal vein during pyelography after nephrostomy: a case report

Pathogenetic factors in vesicoureteral reflux

Contact Info

Product

Resources

About