“…The presence of ulcers in the terminal ileum in a patient without right colon inflammation is specific for CD compared to UC. However, it is important to remember that there are other causes of terminal ileitis, including infection, vasculitis, malignancy, or NSAID induced inflammation [46]. Inflammation, particularly ulceration, stricturing, or fistulization of the upper GI tract or small bowel, is virtually diagnostic of CD over UC, although mild gastritis or duodenitis without ulceration can be present in patients with UC.…”