PWE-072 EUS Fork-tip biopsy versus EUS FNA in the diagnosis of solid pancreatic masses

Oppong, Kofi; Bekkali, Noor; Leeds, John S.; Johnson, Sarah J.; Nayar, Manu; Darné, Antony; Egan, Mark; Bassett, Paul; Haugk, Beate

doi:10.1136/gutjnl-2019-bsgabstracts.303

Cited by 1 publication

(6 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The characteristics of the studies are presented in Table 1 . In all nine articles, one study was a double blind randomized clinical trial [ 13 ] and the others were single blind, randomized clinical trials [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 ]. The studies were performed in the United States (n = 3), in the United Kingdom (n = 2), China (n = 2) and South Korea (n = 2).…”

Section: Resultsmentioning

confidence: 99%

“…All studies included the main outcome, diagnostic accuracy [ 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 ]. Some authors did not find a statistically significant difference between the diagnostic accuracy of the two needle types tested [ 13 , 14 , 15 , 17 , 18 ]; whereas others found that the EUS-FNB needle showed statistically significantly better accuracy than the EUS-FNA needle tested [ 16 , 19 , 20 , 21 ].…”

Section: Resultsmentioning

confidence: 99%

“…According to Tian et al (2018), the negative predictive values, the sensitivity and specificity were, respectively, 50%, 80% and 100% for the EUS-FNB and 82%, 78% and 100% for the EUS-FNA ( p > 0.05), while the positive predictive value was 100% for both methods [ 13 ]. However, Naweed et al (2018) found that the differences were not statistically significant for the sensitivity and specificity between the two groups [ 19 , 20 , 21 , 22 , 23 ].…”

Section: Resultsmentioning

confidence: 99%

“…Two studies looked at the sampling duration and the time added for rapid onsite pathological evaluation (ROSE) [ 20 , 21 , 22 , 24 , 25 , 26 , 27 ]. In the study of Oppong et al (2020), the median time for diagnosis was about 188 s for EUS-FNB vs. 332 s for EUS-FNA ( p < 0.001) [ 21 , 27 , 28 ].…”

Section: Resultsmentioning

confidence: 99%

“… Evaluation of studies quality. Items evaluated as positive for the quality (in green); Negatively evaluated items (in red); The available information in the articles did not allow the evaluation for this item (in yellow) [ 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 ]. …”

Section: Figurementioning

confidence: 99%

See 4 more Smart Citations

Endoscopic Ultrasound Guided Fine Needle Aspiration versus Endoscopic Ultrasound Guided Fine Needle Biopsy for Pancreatic Cancer Diagnosis: A Systematic Review and Meta-Analysis

et al. 2022

View full text Add to dashboard Cite

Introduction: One of the most effective diagnostic tools for pancreatic cancer is endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) or biopsy (EUS-FNB). Several randomized clinical trials have compared different EUS tissue sampling needles for the diagnosis of pancreatic cancer. Objective: To compare the diagnostic accuracy of EUS-guided FNA as EUS-FNB needles for the diagnosis of pancreatic cancer using a systematic review and meta-analysis. Method: A literature review with a meta-analysis was performed according to the PRISMA guide. The databases of PubMed, Cochrane and Google Scholar were used, including studies published between 2011–2021 comparing the diagnostic yield (diagnostic accuracy or probability of positivity, sensitivity, specificity, predictive value) of EUS-FNA and EUS-FNB for the diagnosis of pancreatic cancer. The primary outcome was diagnostic accuracy. Random effect models allowed estimation of the pooled odds ratio with a confidence interval (CI) of 95%. Results: Nine randomized control trials were selected out of 5802 articles identified. Among these, five studies found no statistically significant difference between the EUS-FNA and EUS-FNB, whereas the other four did. The meta-analysis found EUS-FNB accuracy superior to EUS-FNA for the diagnosis of pancreatic cancer with a pooled odds ratio of 1.87 (IC 95%: 1.33–2.63). Conclusion: As compared to EUS-FNA, EUS-FNB seems to improve diagnostic accuracy when applied to suspicious pancreatic lesions.

show abstract