PVA-<i>Nigella sativa</i> nanofibrous mat: antibacterial efficacy and wound healing potentiality

Ali, Ayub; Mohebbullah, Md.; Shahid, Abdus; Alam, Sadikul; Uddin, Md Nur; Miah, Md. Sumon; Jamal, Mohammad Salman Ibna; Khan, Md Shablu

doi:10.1080/00405000.2020.1831168

Cited by 27 publications

(21 citation statements)

References 87 publications

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“…At present, it has a broad scope of utilizations in artificial joints and wound dressings [ 114 ]. Ali et al [ 115 ] used a PVA solution to prepare nanofiber mats with Nigella sativa extract deposited by electrospinning. Wound healing analysis results show that the developed PVA-Nigella sativa nanofibrous mat has good wound healing properties and a short recovery time.…”

Section: Electrospun Nanofibers In Wound Dressingmentioning

confidence: 99%

Electrospun Medicated Nanofibers for Wound Healing: Review

et al. 2021

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With the increasing demand for wound care and treatment worldwide, traditional dressings have been unable to meet the needs of the existing market due to their limited antibacterial properties and other defects. Electrospinning technology has attracted more and more researchers’ attention as a simple and versatile manufacturing method. The electrospun nanofiber membrane has a unique structure and biological function similar to the extracellular matrix (ECM), and is considered an advanced wound dressing. They have significant potential in encapsulating and delivering active substances that promote wound healing. This article first discusses the common types of wound dressing, and then summarizes the development of electrospun fiber preparation technology. Finally, the polymers and common biologically active substances used in electrospinning wound dressings are summarized, and portable electrospinning equipment is also discussed. Additionally, future research needs are put forward.

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Section: Electrospun Nanofibers In Wound Dressingmentioning

confidence: 99%

Electrospun Medicated Nanofibers for Wound Healing: Review

et al. 2021

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“…Antibacterial propeties of with and without leaf extract were checked through Agar disc diffusion method (Ali et al, 2021;Hashmi et al, 2020;Kim et al, 2016) against Staphylococcus aureus (S. aureus) gram-psitive and Esherchia coli (E. coli) gram negative bacteria strains. It was observed that the pure SA/ PVA8 nanofibers as shown in Figure 9 showed the lowest antibacterial properties against gram positive bacteria i.e., 16.02mm while it showed moderate inhibition zone of 18.2mm against gram negative bacteria which is higher than SAMA containing nanofibers.…”

Section: Antibacterial Activitymentioning

confidence: 99%

Antibacterial Sodium Alginate Cosmetic Herbal Electrospun Nanofiber Mask

Saeed¹,

Kishwar²,

Nazir³

et al. 2022

JIS

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V arious companies use different emblems for marketing their cosmetic products. These are incorporation of antibacterial and more importantly ecofriendly agents in cosmetic products etc. Admiration from others and looking beautiful are important factors that builds self-confidence, Abstract | Sodium Alginate (SA) and polyvinyl alcohol (PVA) have earned industrial recognition due to its biocompatible nature. Traditionally, Musa Acuminata (MA) and Hibiscus Rosa Sinensis (HRS) leaves famous for its medicinal value as they contain phytochemicals such as triterpenoids, polyphenols, flavonoids, and alkaloids. Keeping in view and get benefit from their fruitful properties the aim of the study was to develop antibacterial dry sheet nanofiber mask loaded with leaf extracts of MA and HRS as antibacterial agents in SA/PVA nanofibers through electrospinning method, which was just wet before its application. Leaf extracts were used at three concentration levels (0.5, 1, and 1.5 %). Scanning Electron Microscope (SEM) images confirmed the formation of optimized nanofibers with diameter range from ±49 to ±545 nm. It was observed that addition of leaf extract increased the solution conductivity and decrease the surface tension and viscosity. Chemical reactions and presence of functional groups of SA, PVA, HRS and MA were studied by Fourier Transform Infrared Spectroscopy (FTIR). Crystallinity decreased as the SA and leaf extract loaded into the PVA nanofibers as studied through X-ray diffraction (XRD). SAMA nanofibers exhibited highest antibacterial properties against Staphylococcus aureus (gram positive bacteria) than Escherichia coli (gram negative bacteria), while SAHRS nanofibers showed moderate value against both bacteria. It was concluded that prepared antibacterial nanofiber cosmetic mask has an excellent application in medical cosmetic industry.

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“…Based on Ali et al (2020), it had stated about the black seeds extract that had been combined with PVA to produce a nanofibrous mat for wound healing purposes. They had observed that the treatment using the nanofibrous mat indeed showed the wound healed without any infections detected on the wound during the execution of the experiment for seven days.…”

Section: Gross Analysismentioning

confidence: 99%

“…This can be observed by the formation of granulation tissue on the wound site that helps increase the production of interleukins. Moreover, the researchers stated that fatty acids from the black seeds in the nano-fibrous mat helped make collagen that can promote the wound healing process (Ali et al, 2020). Besides that, a study used black seeds oil to treat the socket after removing the teeth in rabbits.…”

Section: Microscopic Analysismentioning

confidence: 99%

“…Some of the bacterial strains such as S. aureus and Enterococcusfaecalis cannot form biofilm due to the existence of the TQ while the gram negative bacteria such as E. Coli were less susceptible to TQ and THQ (Halawani, 2009). The chemical can prevent the oxidative activity of the bacteria and reduce the number of bacteria (Ali et al, 2020).…”

Section: Antimicrobial Analysismentioning

confidence: 99%

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review of black seed extract as an agent in the wound healing process

Zaid

Hanafi

Haris

2021

JoP

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Introduction: Nigella Sativa or Black Cumin is an annual flowering plant that can be used for wound treatment. In the treatment for wound healing, this plant contains many beneficial components that can help with the treatment but this plant utilisation in the medical field is still limited. This review will provide an overview of the advantages when this plant is used in the wound healing treatment. Method: The review was based on the ROSES protocol, and the databases used were ScienceDirect, PubMed, and Google Scholar. After the search, only 11 papers had been chosen to be included in the results and they were divided into four main themes that were used for the analysis of the results. Results: The themes were gross analysis, microscopic analysis, biochemical analysis and antimicrobial analysis. Conclusion: In conclusion, the black seed extract contains several valuable properties, such as antimicrobial and antioxidant properties, which help improve the wound healing process. Further study needs to be done to discover more potential of Nigella Sativa in treating the wound.

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PVA-Nigella sativa nanofibrous mat: antibacterial efficacy and wound healing potentiality

Cited by 27 publications

References 87 publications

Electrospun Medicated Nanofibers for Wound Healing: Review

Electrospun Medicated Nanofibers for Wound Healing: Review

Antibacterial Sodium Alginate Cosmetic Herbal Electrospun Nanofiber Mask

review of black seed extract as an agent in the wound healing process

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