This contribution is dedicated to the analysis of a reliable PV system for specific applications. The reliability study was based on: (1) the RAMS (Reliability, Availability, Maintenance, and Safety) model applied to a PV system by using a simulation SYNTHESIS platform developed by ReliaSoft, and (2) the simulation of the PV system using the SYNTHESIS platform and TM-21 Calculator software developed by ENERGY STAR. The objective of this analysis was to obtain a more stable and long-lasting operation of a PV system regarding reliability, maintainability, availability and degradation of the system.