Pustulose exanthématique aiguë localisée après injections d’héparine calcique

Osché, M.; Gusdorf, L.; Cribier, B.; Scrivener, J.-N.

doi:10.1016/j.annder.2019.09.607

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Cited by 7 publications

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“…Previous presentations of ALEP have typically been localized to the face, neck or chest. We report the first case of ALEP confined to the lower limb as a reaction to an antibiotic, with previous cases either describing inguinal involvement or localized reactions 13–15 …”

Section: Discussionmentioning

confidence: 85%

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Acute localized exanthematous pustulosis of the leg: A case report

Tiong

Leong

Chong

2023

JEADV Clinical Practice

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Section: Discussionmentioning

confidence: 85%

“…We report the first case of ALEP confined to the lower limb as a reaction to an antibiotic, with previous cases either describing inguinal involvement or localized reactions. [13][14][15] The most important treatment is to stop the offending drug. Topical 16 or systemic corticosteroids 17 are occasionally helpful in prolonged cases.…”

Section: Discussionmentioning

confidence: 99%

Acute localized exanthematous pustulosis of the leg: A case report

Tiong

Leong

Chong

2023

JEADV Clinical Practice

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Acute Generalized Exanthematous Pustulosis: Clinical Features, Differential Diagnosis, and Management

et al. 2023

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Acute generalized exanthematous pustulosis (AGEP) is a rare, acute, severe cutaneous adverse reaction mainly attributed to drugs, although other triggers, including infections, vaccinations, ingestion of various substances, and spider bites, have also been described. AGEP is characterized by the development of edema and erythema followed by the eruption of multiple punctate, non-follicular, sterile pustules and subsequent desquamation. AGEP typically has a rapid onset and prompt resolution within a few weeks. The differential diagnoses for AGEP are broad and include infectious, inflammatory, and drug-induced etiologies. Diagnosis of AGEP depends on both clinical and histologic criteria, as cases of overlap with other disease processes have been reported. Management includes removal of the offending drug or treatment of the underlying cause, if necessary, and supportive care, as AGEP is a self-limited disease. This review aims to provide an overview and update on the epidemiology, pathogenesis, reported precipitating factors, differentials, diagnosis, and management of AGEP.

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Heparin

2020

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Pustulose exanthématique aiguë localisée après injections d’héparine calcique

Cited by 7 publications

References 21 publications

Acute localized exanthematous pustulosis of the leg: A case report

Acute localized exanthematous pustulosis of the leg: A case report

Acute Generalized Exanthematous Pustulosis: Clinical Features, Differential Diagnosis, and Management

Heparin

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