Pustular pyoderma gangrenosum

Shankar, Sonal; Sterling, Jane; Rytina, E.

doi:10.1046/j.1365-2230.2003.01418.x

Cited by 25 publications

(12 citation statements)

References 12 publications

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“…However, in one of the reports, two patients with quiescent inflammatory bowel disease developed pustular PG. [10] In our case series, two patients had a combination of pustular and ulcerative lesions in the absence of associated IBD. [2]…”

Section: Etiology and Pathogenesismentioning

confidence: 97%

“…[22] It probably represents a localized, misdirected host-mediated effector cell response to cutaneous tissue antigenically changed by trauma in a patient with altered immune reactivity. [10] Pathergy is seen in nearly 25% of the patients with PG. [4] We have reported that pathergy is more common in PG associated with systemic disease.…”

Section: Etiology and Pathogenesismentioning

confidence: 99%

See 1 more Smart Citation

Pyoderma gangrenosum: An update

Bhat

2012

Indian Dermatol Online J

163

104

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Pyoderma gangrenosum (PG) is an uncommon, distinctive cutaneous ulceration which is usually idiopathic, but may be associated with many systemic disorders. The etipathogenesis of of PG is still not well understood. Clinically it is classified into ulcerative, pustular, bullous and vegetative types. A few atypical and rare variants have also been described. The diagnosis mainly depends on the recognition of evolving clinical features as investigations only assist in the diagnosis. In view of this a few criteria have been proposed for the diagnosis of PG. the treatment mainly consists of corticosteroids and immunosuppressive agents. A few new agents have also been tried in the management.

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Section: Etiology and Pathogenesismentioning

confidence: 97%

Section: Etiology and Pathogenesismentioning

confidence: 99%

Pyoderma gangrenosum: An update

Bhat

2012

Indian Dermatol Online J

163

104

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“…In more than half of cases, the disease is associated with extra-cutaneous diseases, such as inflammatory bowel disease, polyarthritis seronegative or seropositive, and hematologic malignancies. 4,5 Our patient had no underlying disease.…”

Section: Discussionmentioning

confidence: 75%

A case of atypical pyoderma gangrenosum

Vasili

Shkodrani²,

Labinoti³

et al. 2010

J Dermatol Case Rep

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Background: Pyoderma gangrenosum is a rare inflammatory disease of unknown etiology and unspecific histopathology. There are no clear-cut criteria for the diagnosis of this disease. The diagnosis is usually made based on clinical appereance, course of disease and possible, commonly coexisting disorders. In atypical cases the diagnosis is based on exclusion of other causes of similar appearing cutaneous ulcerations.Main observations: The 67-year-old male patient, presented with a 15-year history of painful ulcers and vegetative lesions covered with sero-hemorrhagic and purulent secretions, localized on the dorsal surface of both hands leading to self-amputation of distal phalanges. We report a step-by-step The patient refers to have these complaints for more than 15 years. An extensive diagnostic procedure led to the diagnosis of pyoderma gangrenosum as a diagnosis of exclusion.Conclusion: This report shows an atypical variant of an ulcerative disease. Pyoderma gangrenosum, a diagnosis of exclusion, was sustained based on an extensive diagnostic procedure. In this article we describe the step-by-step approach which let to this diagnosis.

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“…This type of PG is manifest as a more superficial ulceration, which is most frequent on the upper extremities, head or neck. The lesions begin as pustules that spread into plaques that may be studded with pustular lesions, particularly on the dorsum of the hands [8,9]. This variant has also been termed pustular vasculitis of the dorsal hands and neutrophilic dermatoses of the dorsum of the hands (FIGURE 6).…”

Section: Classification Of Pyoderma Gangrenosummentioning

confidence: 99%

Pyoderma gangrenosum: an expert commentary

Jackson¹,

Callen²

2006

Expert Review of Dermatology

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Pyoderma gangrenosum is an inflammatory condition that is characterized by ulcerations of the skin, but may involve other organs. Classically, pyoderma gangrenosum starts as a small pustule that progresses to the classic ulceration with an overhanging violaceous border. Pathergy, the development of cutaneous involvement at sites of trauma, is common. Pyoderma gangrenosum occurs in association with other diseases in approximately 50% of patients and is most commonly associated with inflammatory bowel disease, myeloproliferative disorders and various arthritides. The diagnosis of pyoderma gangrenosum is made by excluding other conditions, such as malignancy, infection, vasculitis and trauma. Treatment of pyoderma gangrenosum involves treatment of an associated disease if present, and topical and/or systemic corticosteroids and/or immunosuppressive therapies.

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Pustular pyoderma gangrenosum

Cited by 25 publications

References 12 publications

Pyoderma gangrenosum: An update

Pyoderma gangrenosum: An update

A case of atypical pyoderma gangrenosum

Pyoderma gangrenosum: an expert commentary

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