Pushing the boundaries of viability: The economic impact of extreme preterm birth

Petrou, Stavros; Henderson, Jane; Bracewell, Melanie A.; Hockley, Christine; Wolke, Dieter; Marlow, Neil

doi:10.1016/j.earlhumdev.2006.01.002

Cited by 62 publications

(49 citation statements)

References 32 publications

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“…39,40 Furthermore, the rigorous costing methodology applied followed national guidance for health economic evaluation purposes. 30,41 A number of caveats must be borne in mind.…”

Section: Strengths and Limitationsmentioning

confidence: 99%

Economic costs associated with moderate and late preterm birth: a prospective population‐based study

Khan

Petrou

Dritsaki

et al. 2015

BJOG

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Objective We sought to determine the economic costs associated with moderate and late preterm birth.Design An economic study was nested within a prospective cohort study.Sample Infants born between 32 +0 and 36 +6 weeks of gestation in the East Midlands of England. A sample of infants born at ≥37 weeks of gestation acted as controls.Methods Data on resource use, estimated from a National Health Service (NHS) and personal social services perspective, and separately from a societal perspective, were collected between birth and 24 months corrected age (or death), and valued in pounds sterling, at 2010-11 prices. Descriptive statistics and multivariable analyses were used to estimate the relationship between gestational age at birth and economic costs.Main outcome measures Cumulative resource use and economic costs over the first two years of life.Results Of all eligible births, 1146 (83%) preterm and 1258 (79%) term infants were recruited. Mean (standard error) total societal costs from birth to 24 months were £12 037 (£1114) and £5823 (£1232) for children born moderately preterm (32 +0-33 +6 weeks of gestation) and late preterm (34 +0 -36 +6 weeks of gestation), respectively, compared with £2056 (£132) for children born at term. The mean societal cost difference between moderate and late preterm and term infants was £4657 (bootstrap 95% confidence interval, 95% CI £2513-6803; P < 0.001). Multivariable regressions revealed that, after controlling for clinical and sociodemographic characteristics, moderate and late preterm birth increased societal costs by £7583 (£874) and £1963 (£337), respectively, compared with birth at full term.Conclusions Moderate and late preterm birth is associated with significantly increased economic costs over the first 2 years of life. Our economic estimates can be used to inform budgetary and service planning by clinical decision-makers, and economic evaluations of interventions aimed at preventing moderate and late preterm birth or alleviating its adverse consequences.

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“…39,40 Furthermore, the rigorous costing methodology applied followed national guidance for health economic evaluation purposes. 30,41 A number of caveats must be borne in mind.…”

Section: Strengths and Limitationsmentioning

confidence: 99%

Economic costs associated with moderate and late preterm birth: a prospective population‐based study

Khan

Petrou

Dritsaki

et al. 2015

BJOG

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“…Liveborn preterm babies drive the need for neonatal care, and in high-income countries half of babies under 25 weeks now survive, but with increasing evidence of major disability. 15 By contrast, in low-income and many middle-income settings, moder ate and late preterm babies do not have even basic care and account for most preterm babies dying. However, from a public health perspective for policy and planning, and from a family loss perspective, both liveborn and stillborn babies born before term are important (fi gure 1).…”

Section: Introductionmentioning

confidence: 99%

National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications

Blencowe¹,

Cousens²,

Oestergaard³

et al. 2012

The Lancet

3,769

2,981

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SummaryBackground Preterm birth is the second largest direct cause of child deaths in children younger than 5 years. Yet, data regarding preterm birth (<37 completed weeks of gestation) are not routinely collected by UN agencies, and no systematic country estimates nor time trend analyses have been done. We report worldwide, regional, and national estimates of preterm birth rates for 184 countries in 2010 with time trends for selected countries, and provide a quantitative assessment of the uncertainty surrounding these estimates.

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“…However, the greatest long-term costs were found to be imposed on the education system (Petrou et al 2001(Petrou et al , 2006. This is reinforced by the findings of a study of ELBW children aged 8 to 11 years, with cohorts drawn from Bavaria, Holland, Canada, and USA, which consistently found that more than half of the ELBW children were experiencing serious educational difficulties (Saigal et al 2003).…”

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confidence: 99%

Educational Needs of School-Aged Children Born Very and Extremely Preterm: A Review

Hornby

Woodward

2009

Educ Psychol Rev

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Recent decades have witnessed dramatically improved survival rates for infants born prematurely, especially those born very and extremely preterm. Follow-up studies concerned with long-term neurodevelopmental outcomes for children born preterm indicate that these children are at high risk for a range of cognitive, learning, neuromotor, and behavioral difficulties. However, to date, most of the existing literature has tended to focus on the medical and developmental impact of preterm birth, with little consideration given to the educational implications. Addressing this research gap is important since cognitive and educational difficulties represent the most commonly occurring cluster of adverse outcomes affecting children born very or extremely preterm, with up to two thirds likely to require educational assistance during their school years. The goal of this review is to provide an overview of existing research findings relating to the educational needs of school-age preterm children. Methodological issues that need to be addressed in future outcome research relating to the developmental and educational needs of very preterm children are also highlighted. Finally, implications of existing findings for educational psychologists, counselors, teachers, and teacher educators are discussed in terms of the roles of society, education systems, schools, and teachers.

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Pushing the boundaries of viability: The economic impact of extreme preterm birth

Cited by 62 publications

References 32 publications

Economic costs associated with moderate and late preterm birth: a prospective population‐based study

Economic costs associated with moderate and late preterm birth: a prospective population‐based study

National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications

Educational Needs of School-Aged Children Born Very and Extremely Preterm: A Review

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