Purtscher-like retinopathy in a paediatric patient with haemolytic uraemic syndrome: A case report and literature review

Benvenuto, Franco; Guillen, S.; Marchiscio, L; Falbo, Jorgelina; Fandiño, Adriana

doi:10.1016/j.oftale.2020.10.007

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…Trombositopenik hastalarda gözlenen arka segment patolojileri retinal kanama, subretinal kanama, vitreus kanaması, koroidal kanama, retina iskemisi, retina damar oklüzyonu, retina neovaskülarizasyonu, proliferatif retinopati, seröz retina dekolmanı, traksiyonel retina dekolmanı, papilödem ve Purtscher benzeri retinopati olarak sıralanabilir. [12][13][14][15][16][17] Bu patolojiler arasında en sık gözleneni ise retina kanamalarıdır. [1] Retina patolojileri sadece trombositopeni etkisiyle değil, ilgili hastalıklara eşlik eden tromboz nedeniyle de ortaya çıkmaktadır.…”

Section: Trombositopenide Retina Bulgularıunclassified

Thrombocytopenia and Retina

2023

Güncel Retina (Current Retina)

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Platelets play a role in blood coagulation and wound healing. Thrombocytopenia is defined as a platelet count of less than 150000/mm3 in the peripheral blood. The most common cause of thrombocytopenia is increased destruction. Ocular involvement is rare in thrombocytopenia, and bleeding is the most common complication. The increased tendency to thrombosis observed in some types of thrombocytopenia causes occlusion in retinal arterioles, and this results in retinal ischemia. Combined systemic and ocular interventions are used in the treatment.

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Section: Trombositopenide Retina Bulgularıunclassified

Thrombocytopenia and Retina

2023

Güncel Retina (Current Retina)

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Severe Adult Still’s Disease Complicated by Purtscher-Like Retinopathy Treated with Intravenous Pulse Methylprednisolone and Tocilizumab

Akiyama

Iwasaki

Tanaka

2021

Case Rep Ophthalmol

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Adult Still’s disease (ASD) is a rare systemic inflammatory disorder in which ocular manifestations have rarely been described. We report a 29-year-old Japanese woman with a rare case of refractory ASD complicated by Purtscher-like retinopathy. She was diagnosed with ASD and started on a high dose of oral prednisolone. Two days after the initiation of the treatment, she presented with blurred vision in the left eye, and the funduscopic examination revealed bilateral Purtscher-like retinopathy. Despite treatment with high-dose oral prednisolone for 2 weeks, she developed macrophage activation syndrome. Considering the severity of ASD, intravenous pulse methylprednisolone therapy and tocilizumab injection were administered. Although all the laboratory data and Purtscher-like retinopathy gradually improved, nerve fiber layer defect (NFLD) in both eyes appeared and visual field defect remained corresponding to the NFLD. In conclusion, Purtscher-like retinopathy might be useful as a poor prognostic factor of ASD, which needs appropriate systemic immunosuppressive treatment. Early detection and long-term follow-up of Purtscher-like retinopathy is important because it has the possibility of developing permanent visual field defect.

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Purtscher-like retinopathy in a paediatric patient with haemolytic uraemic syndrome: A case report and literature review

Cited by 2 publications

References 7 publications

Thrombocytopenia and Retina

Thrombocytopenia and Retina

Severe Adult Still’s Disease Complicated by Purtscher-Like Retinopathy Treated with Intravenous Pulse Methylprednisolone and Tocilizumab

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