Purtscher-like retinopathy after a possible viral infection with lymphadenopathy

Yi, Changxian; Ou, Jiexong; Chen, Jinwei; Hong, Ying; Yu, Qiang

doi:10.1007/s12009-001-0036-7

Cited by 1 publication

(1 citation statement)

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“…It is possible that recurrent osteomyelitis and bilateral foot infections triggered an inflammatory response that led to PLR and sudden-onset bilateral vision loss. Viral illnesses have been associated with PLR following a potentially similar vasculitic mechanism [ 6 , 7 ].…”

Section: Discussionmentioning

confidence: 99%

Purtscher-like retinopathy in a 19-year-old with maturity-onset diabetes of the young: a case report

Javaheri

Hosseini

et al. 2023

J Med Case Reports

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Background We report the first case of Purtscher-like retinopathy in a patient with 17q12 deletion-associated maturity-onset diabetes of the young. Case presentation A 19-year-old diabetic Hispanic male with history of cataracts and toe amputations presented with sudden onset of painless bilateral vision loss for 1 week with no associated trauma. Visual acuity was counting fingers at six feet in both eyes. Dilated retinal examination revealed bilateral peripapillary cotton wool spots and intraretinal hemorrhages, and significant subretinal and intraretinal fluid on optical coherence tomography. Fluorescein angiography revealed arteriolar staining and leakage around the disc with areas of capillary nonperfusion, supporting the diagnosis of Purtscher-like retinopathy. Systemic workup revealed multiple diabetic complications including chronic osteomyelitis of multiple toes, nonhealing diabetic foot ulcers, neurogenic bladder and bowel, and bilateral lower-extremity muscular neuropathies. Genetic evaluation revealed a 17q12 deletion, which is associated with maturity-onset diabetes of the young 5. On follow-up examination, he received a single intravitreal antivascular endothelial growth factor injection in the left eye (off label) for persistent macular edema. Although his retinal edema improved, his visual acuity remained poor. Conclusions The presentation of our patient’s multiple diabetic complications along visual symptoms suggests Purtscher-like retinopathy can be a sequela of uncontrolled diabetes. Purtscher-like retinopathy is a rare but possible consideration in diabetic patients who present with acute-onset vision loss.

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Section: Discussionmentioning

confidence: 99%