Purpura thrombopénique à parvovirus B19 compliqué d'hémorragie cérébroméningée

Tourneux, P.; Jouvencel, P.; Micheau, M; Jouvencel, Anne-Christine; Chateil, J.F.; Barba, Germán Peces; Letavernier, Béatrice; Llanas, Brigitte

doi:10.1016/j.arcped.2004.11.017

Cited by 3 publications

(4 citation statements)

References 11 publications

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“…Le taux de mortalité élevé, de 24 à 57 % selon les séries [4,6,8] (Tableau 4). Cinq patients sur les 14 sont décédés et un patient présente des séquelles neurologiques.…”

Section: Quel Pronostic ?unclassified

“…L'évolution est le plus souvent aiguë et de résolution spontanée [1,4]. À 6 mois, un tiers des enfants ont une thrombopénie persistante et parmi eux 16 % seront en rémission durable à 1 an (série Intercontinental Study Group) [5].…”

Section: Introductionunclassified

“…La plupart des patients ne développent pas de manifestation hémorragique sévère [5]. Les hémorragies intracrâniennes (HIC) sont exceptionnelles (0,1 à 1 % des cas) [5][6][7], mais d'une extrême gravité (mortalité de 24-57 %) [4,6,8,9]. Les facteurs prédictifs d'évolution vers une HIC et les moyens de prévention sont mal connus.…”

Section: Introductionunclassified

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Hémorragie intracrânienne compliquant un purpura thrombopénique immunologique aigu de l’enfant : une étude rétrospective nationale

Sevrez

Thouvenin

Choppard

et al. 2014

Revue d'Oncologie Hématologie Pédiatrique

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“…Le taux de mortalité élevé, de 24 à 57 % selon les séries [4,6,8] (Tableau 4). Cinq patients sur les 14 sont décédés et un patient présente des séquelles neurologiques.…”

Section: Quel Pronostic ?unclassified

Section: Introductionunclassified

See 1 more Smart Citation

Hémorragie intracrânienne compliquant un purpura thrombopénique immunologique aigu de l’enfant : une étude rétrospective nationale

Sevrez

Thouvenin

Choppard

et al. 2014

Revue d'Oncologie Hématologie Pédiatrique

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“…ITP is a benign condition with favorable evolution most of the time. Cerebro-mening ealhaemorrhage, its dreaded complication, rarely occurs (0.1-1% of cases), but is of extreme severity (mortality between 24 and 57%) [3][4][5][6][7][8][9]. In Europe and the USA, several cases have been described for several years with an estimated incidence of 1-12 cases per 100,000 children per year [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Immune Thrombocytopenic Purpura of Children in Black Africa: Two New Observations in Togo

2018

JPNB

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Introduction: Immune thrombocytopenic purpura (ITP) is an auto immunedisorder that is very common in Europe and the USA but ispoorlydescribed in black Africa. Observations: K.A., boy of 5 years 7 months was admitted in 2012 for post-varicella acute ITP with a hemorrhagic syndrome associated with severe isolated thrombocytopenia at 7,000 platelets / mm3. S.D. is a boy of 3 years 8 months admitted in 2015 for ITP which history is marked by a delay in diagnosis despite several consultations. In both cases, complete remission was obtained under prednisone. Discussion: Recently, the rarity of ITP has also been highlighted in the USA in the black race. The probable reasons given were genetic factors, a sub-diagnosis due to the discrimination of the blacks in the accessibility to healthcare, a relative discretion of the petechi as which can go unnoticed on black skin, but also the ignorance of the affection by the practitioners in Togo. Conclusion: ITP is poorly known and poorly reported in Black Africa. The establishment of an ITP registry may increase its knowledge and impact.

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Neurological Manifestations Associated with Parvovirus B19 Infection in Immunocompetent Children: Case Series and Systematic Review

Monteiro

Baía-da-Silva

Silva

et al. 2021

Journal of Tropical Pediatrics

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An increasing number of reports have described human parvovirus B19 infection in association with a variety of neurological manifestations, especially in children. This study assessed the clinical and laboratory outcomes found in a case series of immunocompetent children who tested positive for parvovirus B19 by qualitative polymerase chain reaction assays of cerebrospinal fluid, in a tertiary referral center in the western Brazilian Amazon. We screened 178 children with clinically diagnosed central nervous system infections (meningoencephalitis). Of these, five (2.8%) were positive for parvovirus B19. A literature review also presented herein identified a further 50 cases of parvovirus B19 with neurological manifestations. Thus, even if the classic signs of parvovirus B19 infection are absent, such as the well-known rash, children with signs of neurological infection should also be evaluated for parvovirus B19 infection.

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Purpura thrombopénique à parvovirus B19 compliqué d'hémorragie cérébroméningée

Cited by 3 publications

References 11 publications

Hémorragie intracrânienne compliquant un purpura thrombopénique immunologique aigu de l’enfant : une étude rétrospective nationale

Hémorragie intracrânienne compliquant un purpura thrombopénique immunologique aigu de l’enfant : une étude rétrospective nationale

Immune Thrombocytopenic Purpura of Children in Black Africa: Two New Observations in Togo

Neurological Manifestations Associated with Parvovirus B19 Infection in Immunocompetent Children: Case Series and Systematic Review

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