Abstract:PurposeTo detect the possible safety signal of purine antimetabolites associated with Pneumocystis jirovecii pneumonia through disproportionality analysis in the FDA Adverse Event Reporting System (FAERS) Database.MethodsA case/non‐case retrospective disproportionality analysis was performed in the publicly available FAERS database using AERSmine (2004Q1–2021Q3). Four models were developed to explore the signal strength of PAs among different populations with possible confounding factors. Reporting odds ratio … Show more
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