Purification and characterization of novel antioxidant peptides from duck breast protein hydrolysates

Li, Tingting; Shi, Caiyue; Zhou, Changyu; Sun, Xiaoyi; Yun, Ang; Dong, Xiufang; Huang, Ming; Zhou, Guanghong

doi:10.1016/j.lwt.2020.109215

Cited by 55 publications

(35 citation statements)

References 32 publications

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“…Molecular docking studies revealed that the potential antioxidant activity of both peptides resulted from the interaction of Ser and Thr residues with free radicals. Li et al [ 96 ] characterized the primary sequence as well as the secondary and tertiary structures of duck breast protein, deriving peptides using Nano-LC-ESI-LTQ-Orbitrap MS/MS, NICOLET IS10 FT-IR, and the PEPstr server, respectively. AGPSIVH was the best DPPH • scavenger, whereas FLLPH and LLCVAV were effective ABTS +• scavengers.…”

Section: Antioxidant Peptidesmentioning

confidence: 99%

“…Additionally, LLCVAV proved to have reducing power. Li et al [ 96 ] used FT-IR spectroscopy to estimate the secondary structures of eleven synthesized peptides and suggested that the spatial structure could play a significant role in the antioxidant ability.…”

Section: Antioxidant Peptidesmentioning

confidence: 99%

“…Peptide–food matrix interactions should also be considered, as they can lead to chemical modifications affecting the bioaccessibility and bioavailability of bioactive peptides [ 7 , 97 ]. In this regard, simulated in vitro gastrointestinal (GI) digestion systems are commonly applied for investigation of the release of potentially bioactive peptides from food proteins and for determination of their bioaccessibility [ 81 , 82 ] and the stability of specific antioxidant peptides against simulated GI digestion [ 81 , 82 , 96 , 98 ]. Gallego et al [ 81 ] evaluated the effect of in vitro GI digestion on the antioxidant activity of peptides naturally generated in Spanish dry-cured hams within 12 months of processing.…”

Section: Antioxidant Peptidesmentioning

confidence: 99%

“…Their results showed that the antioxidant activity in the digested samples decreased when measured with DPPH • scavenging activity and ferric-reducing antioxidant power methods, but increased in the ABTS +• scavenging assay. Three novel potent antioxidant peptides AGPSIVH, FLLPH, and LLCVAV were obtained from duck breast protein hydrolysates by Li et al [ 96 ]. The peptides had no toxic effects but exhibited digestive resistance.…”

Section: Antioxidant Peptidesmentioning

confidence: 99%

See 3 more Smart Citations

Current Trends of Bioactive Peptides—New Sources and Therapeutic Effect

Jakubczyk

Karaś

Rybczyńska‐Tkaczyk

et al. 2020

Foods

155

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Generally, bioactive peptides are natural compounds of food or part of protein that are inactive in the precursor molecule. However, they may be active after hydrolysis and can be transported to the active site. Biologically active peptides can also be synthesized chemically and characterized. Peptides have many properties, including antihypertensive, antioxidant, antimicrobial, anticoagulant, and chelating effects. They are also responsible for the taste of food or for the inhibition of enzymes involved in the development of diseases. The scientific literature has described many peptides with bioactive properties obtained from different sources. Information about the structure, origin, and properties of peptides can also be found in many databases. This review will describe peptides inhibiting the development of current diseases, peptides with antimicrobial properties, and new alternative sources of peptides based on the current knowledge and documentation of their bioactivity. All these issues are part of modern research on peptides and their use in current health or technological problems in food production.

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Section: Antioxidant Peptidesmentioning

confidence: 99%

Section: Antioxidant Peptidesmentioning

confidence: 99%

Section: Antioxidant Peptidesmentioning

confidence: 99%

Section: Antioxidant Peptidesmentioning

confidence: 99%

See 2 more Smart Citations

Current Trends of Bioactive Peptides—New Sources and Therapeutic Effect

Jakubczyk

Karaś

Rybczyńska‐Tkaczyk

et al. 2020

Foods

155

View full text Add to dashboard Cite

show abstract

“…Protein hydrolysates (mainly contains antioxidant peptides), derived from natural sources, have gained growing interest as potential natural antioxidants due to their little or no negative side effects, lower molecular weight, easy absorption, high activity, and low cost [ 7 ]. Nowadays, antioxidant protein hydrolysates from various sources, including mushroom [ 8 ], soy [ 9 ], milk [ 10 ], Cyprinus carpio skin gelatin [ 11 ], and duck breast [ 12 ], have been investigated. Regarding the protein sources of bioactive peptides, one of the promising foodstuffs are mushrooms [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Preparation of Antioxidant Protein Hydrolysates from Pleurotus geesteranus and Their Protective Effects on H2O2 Oxidative Damaged PC12 Cells

Liao

Zhu

et al. 2020

Molecules

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Pleurotus geesteranus is a promising source of bioactive compounds. However, knowledge of the antioxidant behaviors of P. geesteranus protein hydrolysates (PGPHs) is limited. In this study, PGPHs were prepared with papain, alcalase, flavourzyme, pepsin, and pancreatin, respectively. The antioxidant properties and cytoprotective effects against oxidative stress of PGPHs were investigated using different chemical assays and H2O2 damaged PC12 cells, respectively. The results showed that PGPHs exhibited superior antioxidant activity. Especially, hydrolysate generated by alcalase displayed the strongest 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity (91.62%), 2,2-azino-bis (3-ethylbenzothia zoline-6-sulfonic acid) (ABTS) radical scavenging activity (90.53%), ferric reducing antioxidant power, and metal ion-chelating activity (82.16%). Analysis of amino acid composition revealed that this hydrolysate was rich in hydrophobic, negatively charged, and aromatic amino acids, contributing to its superior antioxidant properties. Additionally, alcalase hydrolysate showed cytoprotective effects on H2O2-induced oxidative stress in PC12 cells via diminishing intracellular reactive oxygen species (ROS) accumulation by stimulating antioxidant enzyme activities. Taken together, alcalase hydrolysate of P. geesteranus protein can be used as beneficial ingredients with antioxidant properties and protective effects against ROS-mediated oxidative stress.

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Extraction optimization and screening of antioxidant peptides from grass carp meat and synergistic–antagonistic effect

Jia

Zhu

Zhang

et al. 2022

Food Science & Nutrition

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Reactive oxygen species (ROS), for instance hydroxyl free radical, hydrogen peroxide, and singlet oxygen are normal products of cellular respiration or as a response of human body to ultraviolet (UV) radiation, chemical agents, and thermal stress. But overformation or accumulation of ROS will trigger oxidative stress, which is related to many human diseases, such as cardiovascular diseases (Petyaev et al., 2018), cancers (Diehn et al., 2009, diabetes, aging and neurodegenerative diseases (Sarmadi & Ismail, 2010), etc. Therefore, it is

show abstract

Purification and characterization of novel antioxidant peptides from duck breast protein hydrolysates

Cited by 55 publications

References 32 publications

Current Trends of Bioactive Peptides—New Sources and Therapeutic Effect

Current Trends of Bioactive Peptides—New Sources and Therapeutic Effect

Preparation of Antioxidant Protein Hydrolysates from Pleurotus geesteranus and Their Protective Effects on H2O2 Oxidative Damaged PC12 Cells

Extraction optimization and screening of antioxidant peptides from grass carp meat and synergistic–antagonistic effect

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